GLP-1 Interactions Checker: Drug, Food or Drink, One Answer
Pick your GLP-1 medicine, then the medicine, drink or food you want to combine it with. You get the one-line answer from the label and pharmacists, and a link to the full page. 99 pairs checked.
Check a GLP-1 interaction
Every pair we have checked
| Combined with | GLP-1 medicine | Answer | Full page |
|---|---|---|---|
| Actos (pioglitazone) | Victoza | Generally fine together. This pair was Studied; research combined Victoza with metformin plus a glitazone, and Actos is in the glitazone drug class. | Read the answer |
| Adderall | Mounjaro | First, ask your prescriber. No interaction is listed, but each can reduce appetite; ask your prescriber before combining them. | Read the answer |
| Adderall | Ozempic | First, ask your prescriber. No interaction is listed, but each can reduce appetite; ask your prescriber before combining them. | Read the answer |
| Adderall | Semaglutide | First, ask your prescriber. No interaction is listed, but each can reduce appetite; ask your prescriber before combining them. | Read the answer |
| Adderall | Wegovy | First, ask your prescriber. No interaction is listed, but each can reduce appetite; ask your prescriber before combining them. | Read the answer |
| Adderall | Zepbound | First, ask your prescriber. No interaction is listed, but each can reduce appetite; ask your prescriber before combining them. | Read the answer |
| Alcohol | GLP-1 medicines | Fine with care. No alcohol interaction is listed, but drinking can worsen nausea and raise your risk of low blood sugar. | Read the answer |
| Alcohol | Liraglutide | Fine with care. No alcohol interaction is listed, but drinking can worsen nausea and raise your risk of low blood sugar. | Read the answer |
| Alcohol | Mounjaro | Fine with care. No alcohol interaction is listed, but drinking can worsen nausea and raise your risk of low blood sugar. | Read the answer |
| Alcohol | Ozempic | Fine with care. No alcohol interaction is listed, but drinking can worsen nausea and raise your risk of low blood sugar. | Read the answer |
| Alcohol | Rybelsus | Fine with care. No alcohol interaction is listed, but drinking can worsen nausea and raise your risk of low blood sugar. | Read the answer |
| Alcohol | Saxenda | Fine with care. No alcohol interaction is listed, but drinking can worsen nausea and raise your risk of low blood sugar. | Read the answer |
| Alcohol | Semaglutide | Fine with care. No alcohol interaction is listed, but drinking can worsen nausea and raise your risk of low blood sugar. | Read the answer |
| Alcohol | Trulicity | Fine with care. No alcohol interaction is listed, but drinking can worsen nausea and raise your risk of low blood sugar. | Read the answer |
| Alcohol | Victoza | Fine with care. No alcohol interaction is listed, but drinking can worsen nausea and raise your risk of low blood sugar. | Read the answer |
| Alcohol | Wegovy | Fine with care. No alcohol interaction is listed, but drinking can worsen nausea and raise your risk of low blood sugar. | Read the answer |
| Alcohol | Zepbound | Fine with care. No alcohol interaction is listed, but drinking can worsen nausea and raise your risk of low blood sugar. | Read the answer |
| Antidepressants | Mounjaro | Ask your prescriber first. The list shows No interaction involving antidepressants. Speak with your pharmacist about your medicine. | Read the answer |
| Antidepressants | Ozempic | Ask your prescriber first. The list shows No interaction involving antidepressants. Speak with your pharmacist about your medicine. | Read the answer |
| Antidepressants | Semaglutide | Ask your prescriber first. The list shows No interaction involving antidepressants. Speak with your pharmacist about your medicine. | Read the answer |
| Antidepressants | Tirzepatide | Ask your prescriber first. The list shows No interaction involving antidepressants. Speak with your pharmacist about your medicine. | Read the answer |
| Antidepressants | Wegovy | Ask your prescriber first. The list shows No interaction involving antidepressants. Speak with your pharmacist about your medicine. | Read the answer |
| Antidepressants | Zepbound | Ask your prescriber first. The list shows No interaction involving antidepressants. Speak with your pharmacist about your medicine. | Read the answer |
| Birth control pills | Mounjaro | Fine, but use care. For a while, using Mounjaro with birth control pills can reduce their reliability. Add a backup method. | Read the answer |
| Birth control pills | Ozempic | Generally fine when combined. The list shows No interaction. Studies found that semaglutide did not change birth control pill hormone levels. | Read the answer |
| Birth control pills | Semaglutide | Generally fine when combined. The list shows No interaction. Studies found that semaglutide did not change birth control pill hormone levels. | Read the answer |
| Birth control pills | Wegovy | Generally fine when combined. The list shows No interaction. Studies found that semaglutide did not change birth control pill hormone levels. | Read the answer |
| Birth control pills | Zepbound | Fine, but use care. For a while, using Zepbound with birth control pills can reduce their reliability. Add a backup method. | Read the answer |
| Coffee | GLP-1 medicines | Generally fine when combined. The list shows No interaction involving caffeine. Coffee in normal amounts is fine for most adults. | Read the answer |
| Coffee | Liraglutide | Generally fine when combined. The list shows No interaction involving caffeine. Coffee in normal amounts is fine for most adults. | Read the answer |
| Coffee | Mounjaro | Generally fine when combined. The list shows No interaction involving caffeine. Coffee in normal amounts is fine for most adults. | Read the answer |
| Coffee | Ozempic | Generally fine when combined. The list shows No interaction involving caffeine. Coffee in normal amounts is fine for most adults. | Read the answer |
| Coffee | Rybelsus | Fine, but use care. Take Rybelsus only with plain water, then wait before your coffee. Coffee later is fine. | Read the answer |
| Coffee | Saxenda | Generally fine when combined. The list shows No interaction involving caffeine. Coffee in normal amounts is fine for most adults. | Read the answer |
| Coffee | Semaglutide | Generally fine when combined. The list shows No interaction involving caffeine. Coffee in normal amounts is fine for most adults. | Read the answer |
| Coffee | Tirzepatide | Generally fine when combined. The list shows No interaction involving caffeine. Coffee in normal amounts is fine for most adults. | Read the answer |
| Coffee | Trulicity | Generally fine when combined. The list shows No interaction involving caffeine. Coffee in normal amounts is fine for most adults. | Read the answer |
| Coffee | Victoza | Generally fine when combined. The list shows No interaction involving caffeine. Coffee in normal amounts is fine for most adults. | Read the answer |
| Coffee | Wegovy | Generally fine when combined. The list shows No interaction involving caffeine. Coffee in normal amounts is fine for most adults. | Read the answer |
| Coffee | Zepbound | Generally fine when combined. The list shows No interaction involving caffeine. Coffee in normal amounts is fine for most adults. | Read the answer |
| Contrave (naltrexone and bupropion) | Wegovy | Check with your prescriber before combining them. No research covers this pair, so discuss using two weight loss medicines with your prescriber. | Read the answer |
| Insulin | Liraglutide | Fine with care. Because of Insulin, Low blood sugar is more likely. Your doctor may reduce the insulin dose. | Read the answer |
| Insulin | Mounjaro | Fine with care. Because of Insulin, Low blood sugar is more likely. Your doctor may reduce the insulin dose. | Read the answer |
| Insulin | Ozempic | Fine with care. Because of Insulin, Low blood sugar is more likely. Your doctor may reduce the insulin dose. | Read the answer |
| Insulin | Semaglutide | Fine with care. Because of Insulin, Low blood sugar is more likely. Your doctor may reduce the insulin dose. | Read the answer |
| Insulin | Tirzepatide | Fine with care. Because of Insulin, Low blood sugar is more likely. Your doctor may reduce the insulin dose. | Read the answer |
| Insulin | Trulicity | Fine with care. Because of Insulin, Low blood sugar is more likely. Your doctor may reduce the insulin dose. | Read the answer |
| Insulin | Victoza | Fine with care. Because of Insulin, Low blood sugar is more likely. Your doctor may reduce the insulin dose. | Read the answer |
| Insulin | Wegovy | Fine with care. Because of Insulin, Low blood sugar is more likely. Your doctor may reduce the insulin dose. | Read the answer |
| Insulin | Zepbound | Fine with care. Because of Insulin, Low blood sugar is more likely. Your doctor may reduce the insulin dose. | Read the answer |
| Januvia (sitagliptin) | GLP-1 medicines | Usually, these medicines are not combined: a GLP-1 gains no extra sugar lowering from a DPP-4 pill such as Januvia. | Read the answer |
| Januvia (sitagliptin) | Ozempic | Usually, these medicines are not combined: a GLP-1 gains no extra sugar lowering from a DPP-4 pill such as Januvia. | Read the answer |
| Januvia (sitagliptin) | Rybelsus | Usually, these medicines are not combined: a GLP-1 gains no extra sugar lowering from a DPP-4 pill such as Januvia. | Read the answer |
| Januvia (sitagliptin) | Semaglutide | Usually, these medicines are not combined: a GLP-1 gains no extra sugar lowering from a DPP-4 pill such as Januvia. | Read the answer |
| Januvia (sitagliptin) | Trulicity | Usually, these medicines are not combined: a GLP-1 gains no extra sugar lowering from a DPP-4 pill such as Januvia. | Read the answer |
| Jardiance (empagliflozin) | GLP-1 medicines | Fine with care Often prescribed together; if you are sick or eating little, be especially careful about fluids and meals. | Read the answer |
| Jardiance (empagliflozin) | Liraglutide | Fine with care Often prescribed together; if you are sick or eating little, be especially careful about fluids and meals. | Read the answer |
| Jardiance (empagliflozin) | Mounjaro | Fine with care Often prescribed together; if you are sick or eating little, be especially careful about fluids and meals. | Read the answer |
| Jardiance (empagliflozin) | Ozempic | Fine with care Often prescribed together; if you are sick or eating little, be especially careful about fluids and meals. | Read the answer |
| Jardiance (empagliflozin) | Rybelsus | Fine with care Often prescribed together; if you are sick or eating little, be especially careful about fluids and meals. | Read the answer |
| Jardiance (empagliflozin) | Semaglutide | Fine with care Often prescribed together; if you are sick or eating little, be especially careful about fluids and meals. | Read the answer |
| Jardiance (empagliflozin) | Trulicity | Fine with care Often prescribed together; if you are sick or eating little, be especially careful about fluids and meals. | Read the answer |
| Jardiance (empagliflozin) | Victoza | Fine with care Often prescribed together; if you are sick or eating little, be especially careful about fluids and meals. | Read the answer |
| Metformin | Mounjaro | Generally fine to combine. Commonly used together, with Mounjaro tested alongside metformin in its trials. | Read the answer |
| Metformin | Ozempic | Generally fine together Commonly used together; trials tested Ozempic alongside metformin. | Read the answer |
| Metformin | Rybelsus | Generally fine to combine Commonly used together; Rybelsus was tested alongside metformin in its trials. | Read the answer |
| Metformin | Semaglutide | Generally fine together Commonly used together; Semaglutide was tested with metformin during its trials. | Read the answer |
| Metformin | Tirzepatide | Generally fine to combine Commonly used together; its trials included Tirzepatide taken with metformin. | Read the answer |
| Metformin | Trulicity | Generally fine together Commonly used together; Trulicity was tested alongside metformin in its trials. | Read the answer |
| Metformin | Wegovy | Generally fine together Commonly used together; metformin was part of the Wegovy trials. | Read the answer |
| Metformin | Zepbound | Generally fine to combine Commonly used together; its trials tested Zepbound alongside metformin. | Read the answer |
| Noom | Saxenda | Generally fine together Fine together: combine Saxenda with a lower-calorie diet and more activity. | Read the answer |
| Other medicines taken by mouth | Mounjaro | Fine with care. Because Mounjaro slows how the stomach empties, pills can work differently; ask your pharmacist to review each one. | Read the answer |
| Painkillers (ibuprofen, acetaminophen) | Mounjaro | Fine with care No interaction is listed; take extra care with ibuprofen if you are vomiting or dehydrated. | Read the answer |
| Painkillers (ibuprofen, acetaminophen) | Ozempic | Fine with care No interaction is listed; take extra care with ibuprofen if you are vomiting or dehydrated. | Read the answer |
| Painkillers (ibuprofen, acetaminophen) | Semaglutide | Fine with care No interaction is listed; take extra care with ibuprofen if you are vomiting or dehydrated. | Read the answer |
| Painkillers (ibuprofen, acetaminophen) | Tirzepatide | Fine with care No interaction is listed; take extra care with ibuprofen if you are vomiting or dehydrated. | Read the answer |
| Painkillers (ibuprofen, acetaminophen) | Wegovy | Fine with care No interaction is listed; take extra care with ibuprofen if you are vomiting or dehydrated. | Read the answer |
| Painkillers (ibuprofen, acetaminophen) | Zepbound | Fine with care No interaction is listed; take extra care with ibuprofen if you are vomiting or dehydrated. | Read the answer |
| Phentermine | GLP-1 medicines | Avoid together Skip it unless your prescriber plans this pairing; combining weight loss drugs is not recommended by the phentermine label. | Read the answer |
| Phentermine | Mounjaro | Avoid together Skip it unless your prescriber plans this pairing; combining weight loss drugs is not recommended by the phentermine label. | Read the answer |
| Phentermine | Rybelsus | Avoid together Skip it unless your prescriber plans this pairing; combining weight loss drugs is not recommended by the phentermine label. | Read the answer |
| Phentermine | Wegovy | Avoid together Skip it unless your prescriber plans this pairing; combining weight loss drugs is not recommended by the phentermine label. | Read the answer |
| Probiotics | Mounjaro | Combining them is generally fine No interaction is listed, and probiotics have a long history of safe use in healthy people. | Read the answer |
| Probiotics | Ozempic | Combining them is generally fine No interaction is listed, and probiotics have a long history of safe use in healthy people. | Read the answer |
| Probiotics | Semaglutide | Combining them is generally fine No interaction is listed, and probiotics have a long history of safe use in healthy people. | Read the answer |
| Probiotics | Tirzepatide | Combining them is generally fine No interaction is listed, and probiotics have a long history of safe use in healthy people. | Read the answer |
| Probiotics | Wegovy | Combining them is generally fine No interaction is listed, and probiotics have a long history of safe use in healthy people. | Read the answer |
| Probiotics | Zepbound | Combining them is generally fine No interaction is listed, and probiotics have a long history of safe use in healthy people. | Read the answer |
| Slimming World | Saxenda | Generally fine together Fine together: combine Saxenda with a lower-calorie diet and more activity. | Read the answer |
| Thyroid medicine (levothyroxine) | Mounjaro | Fine with care. Mounjaro can change pill absorption. Get your levels checked. | Read the answer |
| Thyroid medicine (levothyroxine) | Rybelsus | Fine with care: In one study, Rybelsus caused levothyroxine levels to rise by 33%; thyroid level checks may be requested by your doctor. | Read the answer |
| Vyvanse | Wegovy | First, ask your prescriber. No interaction is listed, but each can reduce appetite; ask your prescriber before combining them. | Read the answer |
| Wellbutrin (bupropion) | Mounjaro | First, ask your prescriber. No interaction is listed. Ask your pharmacist, because GLP-1 medicines can change the way pills are absorbed. | Read the answer |
| Wellbutrin (bupropion) | Ozempic | First, ask your prescriber. No interaction is listed. Ask your pharmacist, because GLP-1 medicines can change the way pills are absorbed. | Read the answer |
| Wellbutrin (bupropion) | Semaglutide | First, ask your prescriber. No interaction is listed. Ask your pharmacist, because GLP-1 medicines can change the way pills are absorbed. | Read the answer |
| Wellbutrin (bupropion) | Tirzepatide | First, ask your prescriber. No interaction is listed. Ask your pharmacist, because GLP-1 medicines can change the way pills are absorbed. | Read the answer |
| Wellbutrin (bupropion) | Wegovy | First, ask your prescriber. No interaction is listed. Ask your pharmacist, because GLP-1 medicines can change the way pills are absorbed. | Read the answer |
| Wellbutrin (bupropion) | Zepbound | First, ask your prescriber. No interaction is listed. Ask your pharmacist, because GLP-1 medicines can change the way pills are absorbed. | Read the answer |
Every interactions page
All GLP-1 medicines
Ozempic
- Ozempic and Adderall
- Ozempic and Alcohol
- Ozempic and Antidepressants
- Ozempic and Birth Control
- Ozempic and Coffee
- Ozempic and Insulin
- Ozempic and Januvia
- Ozempic and Jardiance
- Ozempic and Metformin
- Ozempic and Nosebleeds
- Ozempic and Over-the-Counter Drugs
- Ozempic and Painkillers
- Ozempic and Probiotics
- Ozempic and Sleepiness
- Ozempic and Stomach Pain
- Ozempic and Trouble Sleeping
- Ozempic and Water Retention
- Ozempic and Wellbutrin
Mounjaro
- Mounjaro and A1C
- Mounjaro and Adderall
- Mounjaro and Alcohol
- Mounjaro and Antidepressants
- Mounjaro and Birth Control
- Mounjaro and Coffee
- Mounjaro and Insulin
- Mounjaro and Jardiance
- Mounjaro and Metformin
- Mounjaro and Other Medications
- Mounjaro and Painkillers
- Mounjaro and Phentermine
- Mounjaro and Probiotics
- Mounjaro and the FDA
- Mounjaro and Thyroid Medication
- Mounjaro and Wellbutrin
Wegovy
- Does Wegovy Affect Birth Control? The Label vs Mounjaro's Warning
- Wegovy and Adderall
- Wegovy and Alcohol
- Wegovy and Antidepressants
- Wegovy and Coffee
- Wegovy and Contrave
- Wegovy and Insulin
- Wegovy and Metformin
- Wegovy and Painkillers
- Wegovy and Phentermine
- Wegovy and Probiotics
- Wegovy and Vyvanse
- Wegovy and Wellbutrin
Semaglutide
- Semaglutide and Adderall
- Semaglutide and Alcohol
- Semaglutide and Antidepressants
- Semaglutide and Birth Control
- Semaglutide and Coffee
- Semaglutide and Insulin
- Semaglutide and Januvia
- Semaglutide and Jardiance
- Semaglutide and Metformin
- Semaglutide and Painkillers
- Semaglutide and Probiotics
- Semaglutide and Wellbutrin