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GLP-1 Decoder

Liraglutide and Alcohol: Is It Safe? Label, Studies

No alcohol interaction is listed, but drinking can worsen nausea and add to low blood sugar risk.

Verdict
Fine with care
Label names it
0 of 2

Check a GLP-1 interaction

Saxenda key facts

How long it remains in your body
100%50%25%0%013 h26 h39 h2.2 d2.7 d50%25%12.5%time after the dose

Half-life about 13 hours: the amount drops by half after 13 h, with about 3% remaining after five half-lives (2.7 d).

Body weight lost in the main trial
Saxenda (SCALE Obesity and Prediabetes)7.4%Placebo3%

For SCALE Obesity and Prediabetes, 56 weeks, the figure was 7.4% of body weight, compared with 3% on placebo.

Sources: FDA label (DailyMed).

Liraglutide and alcohol: the verdict

Fine with care

Alcohol interaction is not listed in the labels for liraglutide (Victoza, Saxenda). Using diabetes medicines with alcohol can lead to abnormally low blood sugar, according to NIAAA.

Details from the liraglutide label

No line on alcohol. If you drink anything, the main warning involves kidney injury from fluid loss. Fluid loss from vomiting or diarrhea may cause kidney injury. Drink fluids and report any heavy fluid loss.

Source: DailyMed FDA label.

What the studies show

Sources: FDA label (DailyMed), niaaa.nih.gov.

The practical rule

Eat something with your drink, and seek help for severe stomach pain that continues.

Source: DailyMed FDA label.

Alcohol with other GLP-1s

None of the 10 GLP-1 labels lists Alcohol in its drug interaction section.

This question also applies to Ozempic, Wegovy, Rybelsus, Mounjaro, Zepbound, Trulicity, Saxenda, and Victoza.