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GLP-1 Decoder

Wegovy and Adderall: Is It Safe? Label, Studies

No interaction is listed, but both can curb appetite; ask your prescriber before combining.

Verdict
Ask your prescriber first
Label names it
No
General caution
Pills absorbed more slowly

Check a GLP-1 interaction

Wegovy in brief

How long it remains in your body
100%50%25%0%07 d14 d21 d28 d35 d50%25%12.5%time after the dose

About 1 week is its half-life. After 7 d, half is gone; after five half-lives (35 d), about 3% remains.

Body weight lost in the main trial
Wegovy (STEP 1)14.9%Placebo2.4%

In STEP 1 over 68 weeks, the body weight figure was 14.9%, compared with 2.4% for placebo.

The price over time
202520262027$1,349.02$0List priceSelf-pay

Monthly prices in US dollars include the list price and self-pay offers. Each comes from the maker's price page.

Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.

Wegovy and Adderall: the verdict

Ask your prescriber first

The Wegovy label's drug interactions section says this word for word:

“WEGOVY causes a delay of gastric emptying and thereby has the potential to impact the absorption of concomitantly administered oral medications. In clinical pharmacology trials”

This is the source: DailyMed FDA label.

What the Wegovy label says

The Wegovy label does not name Adderall. For Adderall, the following lines still apply.

Wegovy label: drug interactions listed
Named in the labelThe riskWhat the label tells doctors
Oral medicinesPills absorbed differentlyIt delays stomach emptying, so other pills may be absorbed in a different way.

This material comes from: Wegovy label (DailyMed).

What the studies show

This is the source: DailyMed FDA label.

The practical rule

  1. Tell your prescriber about both medicines. Mention any racing heart or very little food intake as well.
  2. When you speak with the person prescribing your GLP-1, list every pill you take, including this one.
  3. Find out from your pharmacist whether any of your pills require a steady blood level. You may need these checked when you start or raise the dose.

This is the source: DailyMed FDA label.

Adderall with other GLP-1s

None of the 10 GLP-1 labels mention Adderall in their drug interaction sections. Pills you swallow prompt the same general caution in each, so the answer does not change across the class.

That question also concerns Ozempic, Mounjaro, Zepbound.

This is the source: DailyMed FDA label.