Ozempic and Birth Control: Is It Safe? Label, Studies
No interaction is listed; semaglutide did not change birth control pill hormone levels in studies.
- Verdict
- Generally fine together
- Label names it
- No
- General caution
- Pills absorbed more slowly
Check a GLP-1 interaction
Ozempic: key facts
The drug's half-life is about 1 week. By 7 d, half is gone. About 3% remains when five half-lives have passed (35 d).
During SUSTAIN 1, 30 weeks, people with type 2 diabetes lost 4.7 kg, while those on placebo lost 1.2 kg.
In US dollars, monthly figures include both the list price and available self-pay offers. Each amount comes from the maker's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.
Ozempic and birth control: the verdict
Generally fine together
From the Ozempic label's drug interactions section, word for word:
“OZEMPIC causes a delay of gastric emptying, and thereby has the potential to impact the absorption of concomitantly administered oral medications. In clinical pharmacology trials,”
The DailyMed FDA label is the source.
What the information in Ozempic's label tells you
The Ozempic label does not name birth control pills. The following lines still apply to it.
| Named in the label | The risk | What the label tells doctors |
|---|---|---|
| Oral medicines | Pills absorbed differently | It may change how other pills are absorbed by slowing stomach emptying. |
Source: Ozempic label (DailyMed).
What the studies show
- no change with levonorgestrel or ethinyl estradiol
- absorption of oral medicines: no clinically relevant effect
- The Label's Drug Interactions section:
The DailyMed FDA label is the source.
The practical rule
- Carry on with your pill as usual. If bad vomiting means it may not have absorbed, ask your pharmacist what to do.
- Mention each pill you take, including this one, to the person who prescribes your GLP-1.
- Ask your pharmacist whether any pills you take need steady blood levels. Those may need checking when you start treatment. The same may be needed if you increase the amount.
The DailyMed FDA label is the source.
Birth control with other GLP-1s
Each label's drug interaction section was checked for that same issue.
| Medicine | Birth control pills in the label | Verdict | Page |
|---|---|---|---|
| Ozempic | Not named; general pill caution | Generally fine together | Not listed |
 Wegovy | Not named; general pill caution | Generally fine together | Read the answer |
 Rybelsus | Not named; general pill caution | Not listed | Not listed |
 Mounjaro | Named in the label | Fine with care | Read the answer |
 Zepbound | Named in the label | Fine with care | Read the answer |
 Foundayo | Named in the label | Not listed | Not listed |
 Trulicity | Not named; general pill caution | Not listed | Not listed |
 Saxenda | Not named; general pill caution | Not listed | Not listed |
 Victoza | Not named; general pill caution | Not listed | Not listed |
| Byetta | Named in the label | Not listed | Not listed |
The DailyMed FDA label is the source.