Does Wegovy Affect Birth Control? The Label vs Mounjaro's Warning
No interaction is listed; semaglutide did not change birth control pill hormone levels in studies.
- Verdict
- Generally fine together
- Label names it
- No
- General caution
- Pills absorbed more slowly
Check a GLP-1 interaction
Wegovy facts at a glance
Its half-life is about 1 week: after 7 d, half is gone, and about 3% remains after five half-lives (35 d).
During STEP 1, the 68-week results were 14.9% of body weight, compared with 2.4% on placebo.
Monthly prices in US dollars include the list price and self-pay offers, each taken from the maker's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.
Wegovy and birth control: the verdict
Generally fine together
The Wegovy label gives these exact words in its drug interactions section:
“WEGOVY causes a delay of gastric emptying and thereby has the potential to impact the absorption of concomitantly administered oral medications. In clinical pharmacology trials”
The source is the FDA label (DailyMed).
Guidance from the Wegovy label
Birth control pills are not listed in the Wegovy label. The same statements still apply to it.
| Named in the label | The risk | What the label tells doctors |
|---|---|---|
| Oral medicines | Pills absorbed differently | It slows stomach emptying, which can affect how your body absorbs other pills. |
The source is the Wegovy label (DailyMed).
What the studies show
- ethinyl estradiol or levonorgestrel showed no change
- no clinically relevant change in how oral medicines are absorbed
- In the Drug Interactions label section:
The source is the FDA label (DailyMed).
The practical rule
- Keep taking your pill as usual, and if bad vomiting means it may not have absorbed, ask your pharmacist what to do.
- Tell your GLP-1 prescriber about every pill you take, including this one.
- Find out from your pharmacist if any of your pills require a steady blood level. Those may need a check when you start the medicine or increase how much you take.
The source is the FDA label (DailyMed).
Birth control with other GLP-1s
The drug interaction section of each label was checked for that same point.
| Medicine | Birth control pills in the label | Verdict | Page |
|---|---|---|---|
 Ozempic | Not named; general pill caution | Generally fine together | Read the answer |
| Wegovy | Not named; general pill caution | Generally fine together | Not listed |
 Rybelsus | Not named; general pill caution | Not listed | Not listed |
 Mounjaro | Named in the label | Fine with care | Read the answer |
 Zepbound | Named in the label | Fine with care | Read the answer |
 Foundayo | Named in the label | Not listed | Not listed |
 Trulicity | Not named; general pill caution | Not listed | Not listed |
 Saxenda | Not named; general pill caution | Not listed | Not listed |
 Victoza | Not named; general pill caution | Not listed | Not listed |
| Byetta | Named in the label | Not listed | Not listed |
The source is the FDA label (DailyMed).