Zepbound Cost: With and Without Insurance, Cheapest Route
Zepbound has a list price of $499 to $1,086 per fill before insurance. Self-pay starts at $299 a month (LillyDirect: LillyDirect vial or KwikPen 2.5 mg). With commercial insurance that covers it, the savings card can bring the copay down to $25 for up to a 3-month fill.
- List price
- $499 to $1,086 per fill
- Self-pay from
- $299 a month
- With a savings card
- From $25 for a fill of up to 3 months
- Medicare
- $50 a month
For Zepbound cost, three answers matter: the amount you pay through insurance or Medicare, what self-pay programs charge, and the list price.
Zepbound in brief
The half-life is 5 to 6 days: after 5.5 d, half is gone, and about 3% remains once five half-lives pass (27.5 d).
In SURMOUNT-1 over 72 weeks, 20.9% of body weight was lost, against 3.1% on placebo.
Sources: FDA label (DailyMed).
Zepbound cost: the price table
| Route | Who it is for | What you pay | Limits and dates |
|---|---|---|---|
| List price | Before insurance or any discount | $499 to $1,086 per fill | Not listed |
| Zepbound Savings Program | Commercially insured with Zepbound coverage; government plans excluded | From $25 for a fill of up to 3 months | Up to $1,300 per calendar year is the limit, and each 1-month fill can save up to $100. Ends December 31, 2026 |
| Zepbound savings offer if your plan does not cover it | KwikPen 2.5 mg, commercial plan without coverage | $299 a month | For commercial plans without coverage, a single-dose pen costs $499 each month |
| LillyDirect: LillyDirect vial or KwikPen 2.5 mg | Self-pay, no insurance needed | $299 a month | Not listed |
| LillyDirect: LillyDirect vial or KwikPen 5 mg | Self-pay, no insurance needed | $399 a month | Not listed |
| LillyDirect: doses from 7.5 mg to 15 mg, with a refill within 45 days | Self-pay, no insurance needed | $449 a month | Not listed |
| TrumpRx listing (vial, starting) | Self-pay only, not with insurance | $299 a month | Not listed |
| Medicare GLP-1 Bridge | Medicare Part D, for weight management | $50 a month | July 1, 2026 to December 31, 2027 |
| Walmart Pharmacy: LillyDirect self-pay (lowest dose) | KwikPen | $299 a month | Not listed |
| Walgreens: self-pay with manufacturer savings card | Cash price at the pharmacy | $299 a month | Not listed |
| Amazon Pharmacy: cash-pay | KwikPen, 5 mg | $399 a month | Not listed |
| Amazon Pharmacy: Zepbound Self Pay Journey Program | KwikPen, 7.5 mg to 15 mg | $449 a month | Not listed |
| GoodRx: GoodRx self-pay | KwikPen | $299 a month | Not listed |
| H-E-B Pharmacy: self-pay with manufacturer savings | KwikPen | $299 a month | Not listed |
Prices checked November 2026. Every price links to the source page.
Sources: pricinginfo.lilly.com, zepbound.lilly.com, Eli Lilly, TrumpRx.
Monthly and yearly costs
One year means 12 monthly fills. These totals count on the price staying the same all year.
| Route | Who it is for | Per month | Per year (12 fills) |
|---|---|---|---|
| LillyDirect: LillyDirect vial or KwikPen 2.5 mg | Self-pay, no insurance needed | $299 a month | $3,588 |
| LillyDirect: LillyDirect vial or KwikPen 5 mg | Self-pay, no insurance needed | $399 a month | $4,788 |
| LillyDirect: doses from 7.5 mg to 15 mg, with a refill within 45 days | Self-pay, no insurance needed | $449 a month | $5,388 |
| TrumpRx listing (vial, starting) | Self-pay only, not with insurance | $299 a month | $3,588 |
| Medicare GLP-1 Bridge | Medicare Part D, for weight management | $50 a month | $600 |
| Walmart Pharmacy: LillyDirect self-pay (lowest dose) | KwikPen | $299 a month | $3,588 |
| Walgreens: self-pay with manufacturer savings card | Cash price at the pharmacy | $299 a month | $3,588 |
| Amazon Pharmacy: cash-pay | KwikPen, 5 mg | $399 a month | $4,788 |
| Amazon Pharmacy: Zepbound Self Pay Journey Program | KwikPen, 7.5 mg to 15 mg | $449 a month | $5,388 |
| GoodRx: GoodRx self-pay | KwikPen | $299 a month | $3,588 |
| H-E-B Pharmacy: self-pay with manufacturer savings | KwikPen | $299 a month | $3,588 |
What changes the Zepbound price
- Strength: the self-pay price depends on which strength your prescriber picks. It ranges between $299 a month and $449 a month.
- Coupon prices: GoodRx reports frequent price changes, and prices differ from one pharmacy to another.
Source: investors.goodrx.com.
Zepbound: the lowest-cost route for your coverage
| If you have | Cheapest route | You pay |
|---|---|---|
| Commercial insurance that covers it | Zepbound Savings Program | From $25 for a fill of up to 3 months |
| Commercial insurance that does not cover it | Zepbound savings offer if your plan does not cover it | $299 a month |
| No insurance | LillyDirect: LillyDirect vial or KwikPen 2.5 mg | $299 a month |
| Medicare | Medicare GLP-1 Bridge | $50 a month |
| Medicaid | Your state's Medicaid drug list decides | Zepbound and Medicaid by state |
Zepbound price changes over time
| Month | Price | What it was |
|---|---|---|
| November 2026 | $499 to $1086.37 per fill | List price (list price range) |
| February 2026 | $299 a month | Self-pay price (KwikPen or vial, 2.5 mg) |
| December 2025 | $299 a month | Self-pay price (2.5 mg vial) |
| December 2025 | $449 a month | Self-pay price (7.5 mg to 15 mg vials, Journey Program) |
| June 2025 | $499 a month | Self-pay price (all vial doses, max) |
| February 2025 | $349 a month | Self-pay price (2.5 mg vial) |
| February 2025 | $499 a month | Self-pay price (7.5 mg and 10 mg vials, Journey Program) |
| August 2024 | $399 a month | Self-pay price (2.5 mg vial) |
| November 2023 | $1,059.87 per fill | List price (list price at launch) |
Sources: pricinginfo.lilly.com, prnewswire.com, Eli Lilly, cnbc.com.
Telehealth services that prescribe Zepbound
Mochi Health program
$90 a month
Tirzepatide, compounded
Found
$99 a month
Compounded GLP-1 plan
Ro
$299 a month
Zepbound KwikPen at the starting dose
Noom Med
the monthly price is $299, starting after the first 4 weeks. You pay quarterly
Compounded GLP-1 and GIP through the GLP-1Rx Plus Program
WeightWatchers Med+
$299 a month
Self-pay option for Zepbound
Each price comes from its program's pricing page. We receive no money from any of these programs.
Sources: ro.co, hims.com, noom.com, joinfound.com.