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GLP-1 Decoder

Victoza: Uses, How It Works, Side Effects, Cost, Coverage

Victoza is a daily injection of liraglutide made by Novo Nordisk, first FDA approved in 2010, for type 2 diabetes and heart risk. List price is $543.51 per 2 pens before insurance. Nausea is the most common side effect in its label: 20% vs 5% on placebo.

Active ingredient
liraglutide
Manufacturer
Novo Nordisk
How it is taken
daily injection
First FDA approval
2010
List price
$543.51 per 2 pens
Most common side effect
Nausea 20% vs 5% on placebo
FDA shortage
On the FDA shortage list
Victoza: a GLP-1 pen injector

Victoza at a glance

Time in the body
100%50%25%0%013 h26 h39 h2.2 d2.7 d50%25%12.5%time after the dose

Its half-life is about 13 hours. After 13 h, half is gone, and after five half-lives (2.7 d), about 3% remains.

Weight loss in the main trial
Victoza (LEAD-3)2.5 kgPlacebo1.1 kg

In the LEAD-3 trial for type 2 diabetes over 52 weeks, people lost 2.5 kg, compared with 1.1 kg on placebo.

Sources: FDA label (DailyMed).

Victoza uses and forms

The FDA label provides Victoza uses, forms and warnings. Both your prescriber and the label determine your dose.

Victoza at a glance
What the label says
Approved useWhen used with diet and exercise, it lowers blood sugar in adults and children with type 2 diabetes who are 10 and older.
Approved useIt reduces the risk of heart attack, stroke or heart-related death in adults with type 2 diabetes who also have heart disease.
FormsPrefilled pen
Strengths on the labelthe pen's dose options are 0.6 mg, 1.2 mg, 1.8 mg
Boxed warningThyroid C-cell tumors in rodents were caused by it, according to the boxed warning. It is not known whether this happens in people. Do not take it if you or a family member previously had medullary thyroid cancer (MTC). Do not take it if you have MEN 2.
StorageNew pens should be refrigerated. A pen may remain at room temperature or in the refrigerator for 30 days after its first use.

Sources: FDA label (DailyMed).

Victoza side effects

The label gives the rate of each side effect from its trials, with placebo (a dummy treatment) shown for comparison. All participants were adults who had type 2 diabetes.

Table 1. Adverse reactions were reported in ≥5% of Adult Patients Treated with VICTOZA for Type 2 Diabetes Mellitus
Side effectVictoza 1.2 mgVictoza 1.8 mgPlacebo
Nausea18%20%5%
Diarrhea10%12%4%
Headache11%10%7%
Nasopharyngitis9%10%8%
Decreased appetite10%9%1%
Vomiting6%9%2%

Sources: FDA label (DailyMed).

The label includes these warnings. Thyroid C-cell Tumors risk and Acute Kidney Injury Due to Volume Depletion are among them. Others include Hypoglycemia, Acute Pancreatitis, Severe Gastrointestinal Adverse Reactions, Acute Gallbladder Disease, Hypersensitivity Reactions, and Pulmonary Aspiration During General Anesthesia or Deep Sedation.

These warnings come from the FDA label on DailyMed.

Victoza interactions

Victoza drug interactions on the label
Taken withWhat the label says
Insulin or sulfonylureasCombining it with insulin or a sulfonylurea, such as glipizide or glimepiride, raises your risk of low blood sugar.
Oral medicinesBecause it slows the emptying of your stomach, other pills may be absorbed differently.

Sources: FDA label (DailyMed).

Check a GLP-1 interaction

Victoza cost and coverage

Victoza prices, shown by route
How you payPrice
List price before insurance$543.51 per 2 pens

The November 2026 price check relied on Novo Nordisk pricing.

Alternatives to Victoza

Other medicines for the same purpose as Victoza
MedicineIngredientHow it is takenShared useTrial weight lossSelf-pay from
Ozempicsemaglutideweekly injectionheart risk and type 2 diabetesNot listed$199 per month
Wegovysemaglutideweekly injection or daily tabletheart risk14.9%$149 per month
Rybelsussemaglutidedaily tabletheart risk and type 2 diabetesNot listedNot listed
Mounjarotirzepatideweekly injectionheart risk and type 2 diabetesNot listedNot listed
Trulicitydulaglutideweekly injectionheart risk and type 2 diabetesNot listedNot listed
Byettaexenatidetwice-daily injectiontype 2 diabetesNot listedNot listed

Sources: TrumpRx, FDA label (DailyMed).

The Victoza label and studies

On DailyMed, read the complete Victoza prescribing information.

Every Victoza page

Comparisons with other drugs