Ozempic and Water Retention: What the Label Says
The Ozempic label does not include water retention as a side effect.
- In the label
- Not listed
- Most common in the label
- Nausea 20.3%
Ozempic: key facts
The half-life is about 1 week: after 7 d, half is gone, and about 3% remains after five half-lives (35 d).
During SUSTAIN 1, lasting 30 weeks, people with type 2 diabetes lost 4.7 kg, compared with 1.2 kg on placebo.
The maker's price page lists monthly amounts in US dollars for the list price and self-pay offers.
Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.
Ozempic label: what appears instead
The Ozempic label does not include water retention. These five side effects are listed most often.
| Side effect | Placebo | Ozempic 0.5 mg | Ozempic 1 mg | More than placebo, 1 mg |
|---|---|---|---|---|
| Nausea | 6.1% | 15.8% | 20.3% | +14.2 points |
| Vomiting | 2.3% | 5% | 9.2% | +6.9 points |
| Diarrhea | 1.9% | 8.5% | 8.8% | +6.9 points |
| Abdominal pain | 4.6% | 7.3% | 5.7% | +1.1 points |
| Constipation | 1.5% | 5% | 3.1% | +1.6 points |
Source: Ozempic label (DailyMed).
Source: FDA label (DailyMed).