Victoza and Insulin: Is It Safe? Label, Studies
Low blood sugar is more likely with insulin; your doctor may lower the insulin dose.
- Verdict
- Fine, as long as you are careful
- Label says
- Listed interaction
Check a GLP-1 interaction
Victoza in brief
The half-life is about 13 hours: after 13 h, half of it is gone, and after five half-lives (2.7 d) about 3% is left.
In LEAD-3, over 52 weeks, people with type 2 diabetes lost 2.5 kg versus 1.1 kg on placebo.
Sources: FDA label (DailyMed).
Victoza and insulin: the verdict
Fine, as long as you are careful
Word for word, the drug interactions section of the Victoza label:
“When initiating VICTOZA, consider reducing the dose of concomitantly administered insulin secretagogues (such as sulfonylureas) or insulin to reduce the risk of hypoglycemia [see Warnings”
Source: FDA label (DailyMed).
What the Victoza label tells you
These Victoza label lines concern insulin
| Named in the label | The risk | What the label tells doctors |
|---|---|---|
| Insulin or sulfonylureas | Low blood sugar | Low blood sugar risk goes up when you use it with insulin or a sulfonylurea, including glipizide or glimepiride. Your doctor may lower the doses of these drugs. |
Source: Victoza label (DailyMed).
What research shows
- Label interaction with insulin or sulfonylureas
Source: FDA label (DailyMed).
A rule you can use
- When you start or change doses, check your blood sugar levels more often, and learn the warning signs of low blood sugar.
- Test your blood sugar more often during the first weeks and following each dose increase.
Source: FDA label (DailyMed).
Insulin with other GLP-1s
The same point was checked in each label's drug interaction section.
| Medicine | Insulin in the label | Verdict | Page |
|---|---|---|---|
 Ozempic | Named in the label | Fine, as long as you are careful | Read the answer |
 Wegovy | Named in the label | Fine, as long as you are careful | Read the answer |
 Rybelsus | Named in the label | Not listed | Not listed |
 Mounjaro | Named in the label | Fine, as long as you are careful | Read the answer |
 Zepbound | Named in the label | Fine, as long as you are careful | Read the answer |
 Foundayo | Named in the label | Not listed | Not listed |
 Trulicity | Named in the label | Fine, as long as you are careful | Read the answer |
 Saxenda | Named in the label | Not listed | Not listed |
| Victoza | Named in the label | Fine, as long as you are careful | Not listed |
| Byetta | Named in the label | Not listed | Not listed |
Source: FDA label (DailyMed).