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GLP-1 Decoder

Saxenda and Noom: Using a Program Alongside the Drug

Yes. Noom is not a medicine, so there is nothing to interact. The Saxenda label already pairs the drug with a reduced-calorie diet and more activity, which is what a program like this coaches.

Label names it
No
Drug interaction
None listed
Label pairs it with
Diet and activity

Saxenda: key facts

How long it remains in the body
100%50%25%0%013 h26 h39 h2.2 d2.7 d50%25%12.5%time after the dose

Its half-life is about 13 hours: after 13 h, half is gone, and about 3% remains after five half-lives (2.7 d).

How much weight was lost in its main trial
Saxenda (SCALE Obesity and Prediabetes)7.4%Placebo3%

In SCALE Obesity and Prediabetes, 56 weeks, the results were 7.4% of body weight versus 3% with placebo.

Sources: FDA label (DailyMed).

What a program adds to the drug

The exact wording of the approved use:

“SAXENDA is indicated in combination with a reduced calorie diet and increased physical activity to reduce excess body weight and maintain weight reduction long term”

Source: the FDA label (DailyMed).

Saxenda trial weight loss

Diet and activity counselling was also provided to everyone in these trials, including the placebo group.

Average trial weight loss for each dose group
TrialDose groupAverage weight lostPlacebo or comparisonWeeksWho was in it
SCALE Obesity and PrediabetesLiraglutide 3.0 mg daily7.4%3%56Adults with obesity or overweight who do not have type 2 diabetes

Source: SCALE Obesity and Prediabetes (FDA label (DailyMed)).