Trulicity Hair Loss: Evidence, the Safety Signal, What Helps
The Trulicity label names alopecia as a reported side effect but gives no trial rate for it.
- In the label
- Listed, no rate given
- Label term
- alopecia
A quick Trulicity overview
Its half-life is about 5 days: half disappears after 5 d, while about 3% remains after five half-lives (25 d).
Sources: FDA label (DailyMed).
What the Trulicity label lists instead
The Trulicity label provides no rate for hair loss. The label gives a rate for each of the five side effects that occur most often.
| Side effect | Placebo | Trulicity 0.75 mg | Trulicity 1.5 mg | More than placebo, 1.5 mg |
|---|---|---|---|---|
| Nausea | 5.3% | 12.4% | 21.1% | +15.8 points |
| Vomiting | 2.3% | 6% | 12.7% | +10.4 points |
| Diarrhea | 6.7% | 8.9% | 12.6% | +5.9 points |
| Abdominal Pain | 4.9% | 6.5% | 9.4% | +4.5 points |
| Decreased Appetite | 1.6% | 4.9% | 8.6% | +7 points |
Source: Trulicity label (DailyMed).
Hair loss: a comparison between Trulicity and other GLP-1s
The results in each label came from that drug's trials, which used different groups of people. Treat it as a rough guide.
That table also includes pill forms: Foundayo.
| Medicine | Highest rate in the label | Dose group | Placebo | People in the trials |
|---|---|---|---|---|
 Zepbound | 5% | 5 mg | 1% | Adults with obesity or overweight (weight management) |
 Foundayo | 5% | 17.2 mg | 2% | Adults with obesity or overweight (weight management) |
 Wegovy | 3% | 2.4 mg | 1% | Adults with obesity or overweight (weight management) |
 Ozempic | Listed, no rate given | – | – | – |
 Mounjaro | Listed, no rate given | – | – | – |
| Trulicity | Listed, no rate given | – | – | – |
| Byetta | Listed, no rate given | – | – | – |
 Rybelsus | Not listed | – | – | – |
 Saxenda | Not listed | – | – | – |
 Victoza | Not listed | – | – | – |
Sources: Wegovy label (DailyMed), Zepbound label (DailyMed), Foundayo label (DailyMed).
Source: DailyMed FDA label.
What the label says
On hair loss, the label uses these words exactly:
“procedures requiring general anesthesia or deep sedation Renal: acute renal failure or worsening of chronic renal failure, sometimes requiring hemodialysis Skin and Subcutaneous Tissue: alopecia”
Source: DailyMed FDA label.