Trulicity Heart: How Common, How Long It Lasts, What Helps
The Trulicity label names heart rate as a reported side effect but gives no trial rate for it.
- In the label
- Listed, no rate given
- Label term
- heart rate
A quick look at Trulicity
The half-life is about 5 days. After 5 d, half is gone, and after five half-lives (25 d), about 3% remains.
Sources: FDA label (DailyMed).
What the Trulicity label states instead
The Trulicity label gives no rate for heart effects. Rates are given for the five side effects mentioned most often in the label.
| Side effect | Placebo | Trulicity 0.75 mg | Trulicity 1.5 mg | More than placebo, 1.5 mg |
|---|---|---|---|---|
| Nausea | 5.3% | 12.4% | 21.1% | +15.8 points |
| Vomiting | 2.3% | 6% | 12.7% | +10.4 points |
| Diarrhea | 6.7% | 8.9% | 12.6% | +5.9 points |
| Abdominal Pain | 4.9% | 6.5% | 9.4% | +4.5 points |
| Decreased Appetite | 1.6% | 4.9% | 8.6% | +7 points |
Source of the label: Trulicity label (DailyMed).
Source of the label: FDA label (DailyMed).
What the Trulicity label says
For heart effects, the label provides this passage word for word:
“In adult patients, TRULICITY 0.75 mg and 1.5 mg resulted in a mean increase in heart rate (HR) of 2-4 beats per minute (bpm).”
Source of the label: FDA label (DailyMed).