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GLP-1 Decoder

Liraglutide Hair Loss: How Common, How Long It Lasts

The liraglutide labels do not list hair loss as a side effect. What people mean by it: more hair than usual coming out. Labels call it hair loss or alopecia.

In the label
Not listed
Most common in the label
Nausea 20%

A quick look at Saxenda

How long it remains in your body
100%50%25%0%013 h26 h39 h2.2 d2.7 d50%25%12.5%time after the dose

Its half-life is about 13 hours: after 13 h, half is gone, and after five half-lives (2.7 d), about 3% remains.

Weight loss in its main trial
Saxenda (SCALE Obesity and Prediabetes)7.4%Placebo3%

In SCALE Obesity and Prediabetes, 56 weeks: the figure was 7.4% of body weight, versus 3% on placebo.

Sources: FDA label (DailyMed).

What the Victoza label lists instead

The Victoza label does not list hair loss. Here are the five most common side effects it lists.

Table 1. Each listed adverse reaction was reported in ≥5% of Adult Patients Treated with VICTOZA for Type 2 Diabetes Mellitus
Side effectPlaceboVictoza 1.2 mgVictoza 1.8 mgMore than placebo, 1.8 mg
Nausea5%18%20%+15 points
Diarrhea4%10%12%+8 points
Headache7%11%10%+3 points
Nasopharyngitis8%9%10%+2 points
Decreased appetite1%10%9%+8 points

Taken from the Victoza label (DailyMed).

How hair loss on liraglutide compares with other GLP-1s

Each label covers its own trials, which included different groups of people. Use this as a rough guide.

The table also includes the Foundayo pill forms.

Hair loss across GLP-1 labels
MedicineHighest rate in the labelDose groupPlaceboPeople in the trials
Zepbound5%5 mg1%Adults with obesity or overweight (weight management)
Foundayo5%17.2 mg2%Adults with obesity or overweight (weight management)
Wegovy3%2.4 mg1%Adults with obesity or overweight (weight management)
OzempicListed, no rate given–––
MounjaroListed, no rate given–––
TrulicityListed, no rate given–––
ByettaListed, no rate given–––
RybelsusNot listed–––
SaxendaNot listed–––
VictozaNot listed–––

Sources: Wegovy label (DailyMed), Zepbound label (DailyMed), Foundayo label (DailyMed).

Source: FDA label (DailyMed).