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GLP-1 Decoder

Trulicity Muscle Loss: How Common, How Long It Lasts

The Trulicity label does not include muscle loss as a side effect. What people mean by it: losing muscle along with fat while losing weight.

In the label
Not listed
Most common in the label
Nausea 21.1%

Trulicity: a quick view

How long it remains in your body
100%50%25%0%05 d10 d15 d20 d25 d50%25%12.5%time after the dose

Its half-life is about 5 days: after 5 d, half is gone, and after five half-lives (25 d), about 3% remains.

Sources: FDA label (DailyMed).

The Trulicity label lists these instead

The Trulicity label does not include muscle loss. The label lists these five side effects most often.

Adverse Reactions in Pool of Placebo-Controlled Trials That Occurred in at least 5% of TRULICITY-Treated Adult Patients with Type 2 Diabetes Mellitus, Table 1
Side effectPlaceboTrulicity 0.75 mgTrulicity 1.5 mgMore than placebo, 1.5 mg
Nausea5.3%12.4%21.1%+15.8 points
Vomiting2.3%6%12.7%+10.4 points
Diarrhea6.7%8.9%12.6%+5.9 points
Abdominal Pain4.9%6.5%9.4%+4.5 points
Decreased Appetite1.6%4.9%8.6%+7 points

Source: Trulicity label (DailyMed).

Source: FDA label (DailyMed).