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GLP-1 Decoder

Ozempic Hair Loss: How Common, How Long It Lasts, What Helps

The Ozempic label names alopecia as a reported side effect but gives no trial rate for it.

In the label
Listed, no rate given
Label term
alopecia

Ozempic: key facts

How long it remains in the body
100%50%25%0%07 d14 d21 d28 d35 d50%25%12.5%time after the dose

The half-life is about 1 week: after 7 d, half has cleared, and five half-lives (35 d) leave about 3%.

Weight reduction in its main trial
Ozempic (SUSTAIN 1)4.7 kgPlacebo1.2 kg

In the 30-week SUSTAIN 1 trial for type 2 diabetes, 4.7 kg was lost compared with 1.2 kg on placebo.

Cost over time
202520262027$1,027.51$0List priceSelf-pay

The maker's price page lists monthly list prices and self-pay offers in US dollars, with each figure taken from that page.

Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.

What the Ozempic label lists instead

Hair loss has no rate in the Ozempic label. Five side effects appear most often on its list, each with a rate.

Table 1. Type 2 Diabetes Mellitus: Adverse Reactions Seen in Placebo-Controlled Trials Reported in ≥5% of OZEMPIC-Treated Patients
Side effectPlaceboOzempic 0.5 mgOzempic 1 mgMore than placebo, 1 mg
Nausea6.1%15.8%20.3%+14.2 points
Vomiting2.3%5%9.2%+6.9 points
Diarrhea1.9%8.5%8.8%+6.9 points
Abdominal pain4.6%7.3%5.7%+1.1 points
Constipation1.5%5%3.1%+1.6 points

From: Ozempic label (DailyMed).

Hair loss with other GLP-1s

Labels each cover their own trials, which were carried out in different groups of people. Treat it as a rough guide.

That table also includes Foundayo pill forms.

Hair loss across GLP-1 labels
MedicineHighest rate in the labelDose groupPlaceboPeople in the trials
Zepbound5%5 mg1%Adults with obesity or overweight (weight management)
Foundayo5%17.2 mg2%Adults with obesity or overweight (weight management)
Wegovy3%2.4 mg1%Adults with obesity or overweight (weight management)
OzempicListed, no rate given–––
MounjaroListed, no rate given–––
TrulicityListed, no rate given–––
ByettaListed, no rate given–––
RybelsusNot listed–––
SaxendaNot listed–––
VictozaNot listed–––

Label sources: Wegovy label (DailyMed), Zepbound label (DailyMed), Foundayo label (DailyMed).

Source: FDA label (DailyMed).