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GLP-1 Decoder

Wegovy Hair Loss: How Common, How Long It Lasts, What Helps

Yes. In the Wegovy trials, 6% of people on 7.2 mg had hair loss, against 1% on placebo: about 6 times the placebo rate.

In the Wegovy label
Yes, with a rate
On Wegovy 7.2 mg
6%
On placebo
1%

Wegovy facts at a glance

How long it remains in your body
100%50%25%0%07 d14 d21 d28 d35 d50%25%12.5%time after the dose

The half-life is about 1 week. After 7 d, half is gone, and about 3% remains after five half-lives (35 d).

Body weight lost in the main trial
Wegovy (STEP 1)14.9%Placebo2.4%

Weight lost in STEP 1 after 68 weeks was 14.9%, versus 2.4% with placebo

Prices over time
202520262027$1,349.02$0List priceSelf-pay

Monthly prices in US dollars include the list price and self-pay offers. Each comes from the maker's price page.

Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.

Compared with placebo, how often does it appear on Wegovy?

The Wegovy hair loss results from the label trials are broken down by dose group. That same trial includes a placebo group for comparison.

Hair loss that the Wegovy label reports
Medicine and doseHair lossPlaceboMore than placeboPeople in the trials
Wegovy 2.4 mg3%1%+2 pointsAdults with obesity or overweight (weight management)
Wegovy 2.4 mg3%1%+2 pointsAdults with obesity (7.2 mg dose trials)
Wegovy 7.2 mg6%1%+5 pointsAdults with obesity (7.2 mg dose trials)
Wegovy 2.4 mg4%0%+4 pointsChildren 12 and older with obesity

Source: Wegovy label (DailyMed).

Other GLP-1s and hair loss

Each label covers its own trials, which used different groups of people. Consider it a rough guide.

That table includes the pill form Foundayo as well.

Hair loss across GLP-1 labels
MedicineHighest rate in the labelDose groupPlaceboPeople in the trials
Zepbound5%5 mg1%Adults with obesity or overweight (weight management)
Foundayo5%17.2 mg2%Adults with obesity or overweight (weight management)
Wegovy3%2.4 mg1%Adults with obesity or overweight (weight management)
OzempicListed, no rate given–––
MounjaroListed, no rate given–––
TrulicityListed, no rate given–––
ByettaListed, no rate given–––
RybelsusNot listed–––
SaxendaNot listed–––
VictozaNot listed–––

Sources: Wegovy label (DailyMed), Zepbound label (DailyMed), Foundayo label (DailyMed).

Source: FDA label (DailyMed).

What the Wegovy label says

Word for word, the label lists hair loss:

“In clinical trials with WEGOVY 7.2 mg injection, hair loss was reported in 5.8% of patients treated with WEGOVY 7.2 mg (8.4% female, 0.2% male),”

Source: FDA label (DailyMed).