Semaglutide Hair Loss: How Common, How Long It Lasts
Yes. Hair loss is listed in the Wegovy label at 3% on 2.4 mg. Placebo in the Wegovy trials: 1%.
- Labels that list it
- 2 of 3
- Highest rate
- 3% Wegovy
Wegovy: key facts
Its half-life is about 1 week: after 7 days, half is gone, and after five half-lives (35 days), about 3% remains.
In STEP 1, the 68-week result was 14.9% of body weight, versus 2.4% with placebo.
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Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.
On semaglutide vs placebo: how often it appears
The label trials show Semaglutide hair loss by dose group. The placebo group served as the comparison group in that same trial.
| Medicine and dose | Hair loss | Placebo | More than placebo | People in the trials |
|---|---|---|---|---|
| Wegovy 2.4 mg | 3% | 1% | +2 points | Adults with obesity or overweight (weight management) |
| Wegovy 2.4 mg | 3% | 1% | +2 points | Adults with obesity (7.2 mg dose trials) |
| Wegovy 7.2 mg | 6% | 1% | +5 points | Adults with obesity (7.2 mg dose trials) |
| Wegovy 2.4 mg | 4% | 0% | +4 points | Children 12 and older with obesity |
Source: Wegovy label (DailyMed).
Other GLP-1s and hair loss
The labels describe different trials with different groups of people. Think of it as a rough guide.
The pill forms are also included in the table: Foundayo.
| Medicine | Highest rate in the label | Dose group | Placebo | People in the trials |
|---|---|---|---|---|
| 5% | 5 mg | 1% | Adults with obesity or overweight (weight management) | |
| 5% | 17.2 mg | 2% | Adults with obesity or overweight (weight management) | |
| 3% | 2.4 mg | 1% | Adults with obesity or overweight (weight management) | |
| Listed, no rate given | – | – | – | |
| Listed, no rate given | – | – | – | |
| Listed, no rate given | – | – | – | |
| Byetta | Listed, no rate given | – | – | – |
| Not listed | – | – | – | |
| Not listed | – | – | – | |
| Not listed | – | – | – |
Sources: Wegovy label (DailyMed), Zepbound label (DailyMed), Foundayo label (DailyMed).
Source: FDA label (DailyMed).
What the Wegovy label says
The label mentions hair loss in these exact words:
“In clinical trials with WEGOVY 7.2 mg injection, hair loss was reported in 5.8% of patients treated with WEGOVY 7.2 mg (8.4% female, 0.2% male),”
Source: FDA label (DailyMed).