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GLP-1 Decoder

Semaglutide Hair Loss: How Common, How Long It Lasts

Yes. Hair loss is listed in the Wegovy label at 3% on 2.4 mg. Placebo in the Wegovy trials: 1%.

Labels that list it
2 of 3
Highest rate
3% Wegovy

Wegovy: key facts

How long it takes to leave the body
100%50%25%0%07 d14 d21 d28 d35 d50%25%12.5%time after the dose

Its half-life is about 1 week: after 7 days, half is gone, and after five half-lives (35 days), about 3% remains.

Weight lost in the main trial
Wegovy (STEP 1)14.9%Placebo2.4%

In STEP 1, the 68-week result was 14.9% of body weight, versus 2.4% with placebo.

Costs over time
202520262027$1,349.02$0List priceSelf-pay

Monthly prices in US dollars include list prices and self-pay offers. Every figure comes from the maker's price page.

Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.

On semaglutide vs placebo: how often it appears

The label trials show Semaglutide hair loss by dose group. The placebo group served as the comparison group in that same trial.

Semaglutide labels list hair loss
Medicine and doseHair lossPlaceboMore than placeboPeople in the trials
Wegovy 2.4 mg3%1%+2 pointsAdults with obesity or overweight (weight management)
Wegovy 2.4 mg3%1%+2 pointsAdults with obesity (7.2 mg dose trials)
Wegovy 7.2 mg6%1%+5 pointsAdults with obesity (7.2 mg dose trials)
Wegovy 2.4 mg4%0%+4 pointsChildren 12 and older with obesity

Source: Wegovy label (DailyMed).

Other GLP-1s and hair loss

The labels describe different trials with different groups of people. Think of it as a rough guide.

The pill forms are also included in the table: Foundayo.

Hair loss across GLP-1 labels
MedicineHighest rate in the labelDose groupPlaceboPeople in the trials
Zepbound5%5 mg1%Adults with obesity or overweight (weight management)
Foundayo5%17.2 mg2%Adults with obesity or overweight (weight management)
Wegovy3%2.4 mg1%Adults with obesity or overweight (weight management)
OzempicListed, no rate given–––
MounjaroListed, no rate given–––
TrulicityListed, no rate given–––
ByettaListed, no rate given–––
RybelsusNot listed–––
SaxendaNot listed–––
VictozaNot listed–––

Sources: Wegovy label (DailyMed), Zepbound label (DailyMed), Foundayo label (DailyMed).

Source: FDA label (DailyMed).

What the Wegovy label says

The label mentions hair loss in these exact words:

“In clinical trials with WEGOVY 7.2 mg injection, hair loss was reported in 5.8% of patients treated with WEGOVY 7.2 mg (8.4% female, 0.2% male),”

Source: FDA label (DailyMed).