Wegovy Muscle Loss: How Much Lean Mass Is Lost
The Wegovy label does not mention muscle loss as a side effect. What people mean by it: losing muscle along with fat while losing weight.
- In the label
- Not listed
- Most common in the label
- Nausea 44%
Wegovy: a quick view
A dose has a half-life of about 1 week. After 7 d, half is gone; about 3% remains after five half-lives (35 d).
Over 68 weeks in STEP 1, weight loss reached 14.9% of body weight, versus 2.4% on placebo.
Each month’s prices in US dollars include the list price and self-pay offers. Both come from the maker's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.
Information listed on the Wegovy label instead
The Wegovy label does not mention muscle loss. These five side effects are the ones it lists most often.
| Side effect | Placebo | Wegovy 2.4 mg | More than placebo |
|---|---|---|---|
| Nausea | 16% | 44% | +28 points |
| Diarrhea | 16% | 30% | +14 points |
| Vomiting | 6% | 24% | +18 points |
| Constipation | 11% | 24% | +13 points |
| Abdominal Pain | 10% | 20% | +10 points |
Source: Wegovy label (DailyMed).
Source: DailyMed FDA label.