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GLP-1 Decoder

Wegovy Butt: How Common, How Long It Lasts, What Helps

The Wegovy label does not list butt changes as a side effect. What people mean by it: a flatter or saggier buttock area after fast weight loss.

In the label
Not listed
Most common in the label
Nausea 44%

A quick look at Wegovy

Time in the body
100%50%25%0%07 d14 d21 d28 d35 d50%25%12.5%time after the dose

Its half-life is about 1 week. After 7 d, half is gone, and about 3% remains after five half-lives (35 d).

Main trial weight loss
Wegovy (STEP 1)14.9%Placebo2.4%

The STEP 1 comparison covered 68 weeks: 14.9% of body weight compared with 2.4% with placebo.

Costs over time
202520262027$1,349.02$0List priceSelf-pay

In US dollars, monthly figures include the list price and self-pay offers. Each figure comes from the maker's price page.

Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.

What the Wegovy label includes instead

The Wegovy label does not list butt changes. In the label, five side effects appear most often.

Table 3. WEGOVY 2.4 mg in Injection-treated Adults (Obesity, or Overweight for Weight Reduction): Adverse Reactions (≥2%) seen at rates Greater Than Placebo
Side effectPlaceboWegovy 2.4 mgMore than placebo
Nausea16%44%+28 points
Diarrhea16%30%+14 points
Vomiting6%24%+18 points
Constipation11%24%+13 points
Abdominal Pain10%20%+10 points

Source cited: Wegovy label (DailyMed).

Source: FDA label (DailyMed).