Ozempic Muscle Loss: How Common, How Long It Lasts
The Ozempic label does not list muscle loss as a side effect. What people mean by it: losing muscle along with fat while losing weight.
- In the label
- Not listed
- Most common in the label
- Nausea 20.3%
A quick look at Ozempic
Its half-life is about 1 week: after 7 d, half is gone, while about 3% remains after five half-lives (35 d).
In the 30-week SUSTAIN 1 trial of type 2 diabetes, weight loss was 4.7 kg, compared with 1.2 kg on placebo.
Monthly prices in US dollars show list prices and self-pay offers, with each taken from the maker's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.
The Ozempic label: what it includes instead
The Ozempic label does not list muscle loss. These five side effects appear most often on the label.
| Side effect | Placebo | Ozempic 0.5 mg | Ozempic 1 mg | More than placebo, 1 mg |
|---|---|---|---|---|
| Nausea | 6.1% | 15.8% | 20.3% | +14.2 points |
| Vomiting | 2.3% | 5% | 9.2% | +6.9 points |
| Diarrhea | 1.9% | 8.5% | 8.8% | +6.9 points |
| Abdominal pain | 4.6% | 7.3% | 5.7% | +1.1 points |
| Constipation | 1.5% | 5% | 3.1% | +1.6 points |
Source: Ozempic label (DailyMed).
Source: FDA label (DailyMed).