Mounjaro Muscle Loss: How Common, How Long It Lasts
The Mounjaro label does not include muscle loss as a side effect. What people mean by it: losing muscle along with fat while losing weight.
- In the label
- Not listed
- Most common in the label
- Nausea 18%
Mounjaro: a quick summary
With a half-life of about 5 days, the amount falls by half after 5 d. About 3% remains following five half-lives (25 d).
In the 40-week SURPASS-1 trial of type 2 diabetes, participants lost 7.8 kg, compared with 1 kg on placebo.
The monthly price points in US dollars are list prices and self-pay offers. These came from the maker's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, pricinginfo.lilly.com.
What the Mounjaro label includes instead
The Mounjaro label does not include muscle loss. These five are the side effects it lists most often.
| Side effect | Placebo | Mounjaro 5 mg | Mounjaro 10 mg | Mounjaro 15 mg | More than placebo, 15 mg |
|---|---|---|---|---|---|
| Nausea | 4% | 12% | 15% | 18% | +14 points |
| Diarrhea | 9% | 12% | 13% | 17% | +8 points |
| Decreased Appetite | 1% | 5% | 10% | 11% | +10 points |
| Vomiting | 2% | 5% | 5% | 9% | +7 points |
| Dyspepsia | 3% | 8% | 8% | 5% | +2 points |
Source: Mounjaro label (DailyMed).
According to the FDA label (DailyMed).