Saxenda Muscle Loss: How Common, How Long It Lasts
The Saxenda label does not mention muscle loss as a side effect. What people mean by it: losing muscle along with fat while losing weight.
- In the label
- Not listed
- Most common in the label
- Nausea 39.3%
A quick look at Saxenda
Half-life about 13 hours: after 13 h, half is gone, and five half-lives (2.7 d) leave about 3% behind.
During SCALE Obesity and Prediabetes, 56 weeks, the treatment group lost 7.4% of body weight, while the placebo group lost 3%.
Sources: FDA label (DailyMed).
What shows up in the Saxenda label instead
The Saxenda label does not mention muscle loss. The label most often lists these five side effects.
| Side effect | Placebo | Saxenda Saxenda | More than placebo |
|---|---|---|---|
| Nausea | 13.8% | 39.3% | +25.5 points |
| Diarrhea | 9.9% | 20.9% | +11 points |
| Constipation | 8.5% | 19.4% | +10.9 points |
| Vomiting | 3.9% | 15.7% | +11.8 points |
| Injection Site Reaction | 10.5% | 13.9% | +3.4 points |
Source: Saxenda label (DailyMed).
Source: FDA label (DailyMed).