Semaglutide Dizziness: How Common, How Long It Lasts
Yes. Dizziness is listed in the Wegovy label at 8% on 2.4 mg. Placebo in the Wegovy trials: 4%.
- Labels that list it
- 2 of 3
- Highest rate
- 8% Wegovy
Wegovy in brief
The half-life is about 1 week. After 7 d, half is gone, while about 3% remains after five half-lives (35 d).
At STEP 1 over 68 weeks, the figure was 14.9% of body weight, versus 2.4% on placebo.
The maker's price page gives monthly price points in US dollars for both list prices and self-pay offers.
Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.
How often it happens with semaglutide compared with placebo
Semaglutide dizziness is reported in the label trials by dose group. The same trial uses placebo as its comparison group.
| Medicine and dose | Dizziness | Placebo | More than placebo | People in the trials |
|---|---|---|---|---|
| Wegovy 2.4 mg | 8% | 4% | +4 points | Adults with obesity or overweight (weight management) |
| Wegovy 2.4 mg | 5% | 1% | +4 points | Adults with obesity (7.2 mg dose trials) |
| Wegovy 7.2 mg | 6% | 1% | +5 points | Adults with obesity (7.2 mg dose trials) |
| Wegovy 2.4 mg | 8% | 3% | +5 points | Children 12 and older with obesity |
Source: Wegovy label (DailyMed).
Dizziness rates: semaglutide compared with other GLP-1s
Each label describes its own trials, and the trial groups vary. Use this as a rough guide.
| Medicine | Highest rate in the label | Dose group | Placebo | People in the trials |
|---|---|---|---|---|
| Byetta | 9% | all doses | 6% | Adults with type 2 diabetes |
| 8% | 2.4 mg | 4% | Adults with obesity or overweight (weight management) | |
| 6.9% | all doses | 5% | Adults with obesity or overweight (weight management) | |
| 5% | 10 mg | 2% | Adults with obesity or overweight (weight management) | |
| Listed, no rate given | – | – | – | |
| Listed, no rate given | – | – | – | |
| Not listed | – | – | – | |
| Not listed | – | – | – | |
| Not listed | – | – | – | |
| Not listed | – | – | – |
Sources: Wegovy label (DailyMed), Zepbound label (DailyMed), Saxenda label (DailyMed), Byetta label (DailyMed).
Source: FDA label on DailyMed.
Ozempic label words
Dizziness appears in the label word for word:
“Other adverse reactions with a frequency of >0.4% were associated with OZEMPIC include fatigue, dysgeusia and dizziness.”
Source: FDA label on DailyMed.