Ozempic and High Blood Pressure: Does It Lower BP? Is It Safe?
The Ozempic label does not list blood pressure as a side effect. What people mean by it: changes in blood pressure, including low blood pressure that can make you feel faint.
- In the label
- Not listed
- Most common in the label
- Nausea 20.3%
Ozempic: key facts
Its half-life is about 1 week: by 7 d, half has cleared, while about 3% remains by 35 d, which equals five half-lives.
The 30-week SUSTAIN 1 trial in type 2 diabetes showed 4.7 kg lost, compared with 1.2 kg on placebo
Monthly prices in US dollars include the list price and self-pay offers, each taken from the maker's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.
What the Ozempic label lists instead
The Ozempic label does not list blood pressure. It most often lists these five side effects.
| Side effect | Placebo | Ozempic 0.5 mg | Ozempic 1 mg | More than placebo, 1 mg |
|---|---|---|---|---|
| Nausea | 6.1% | 15.8% | 20.3% | +14.2 points |
| Vomiting | 2.3% | 5% | 9.2% | +6.9 points |
| Diarrhea | 1.9% | 8.5% | 8.8% | +6.9 points |
| Abdominal pain | 4.6% | 7.3% | 5.7% | +1.1 points |
| Constipation | 1.5% | 5% | 3.1% | +1.6 points |
Source: Ozempic label (DailyMed).
Other GLP-1s and blood pressure
Each label covers its own trials, which involved different groups of people. Use it as a rough guide.
| Medicine | Highest rate in the label | Dose group | Placebo | People in the trials |
|---|---|---|---|---|
 Zepbound | 2% | 15 mg | 0% | Adults with obesity or overweight (weight management) |
 Wegovy | Listed, no rate given | – | – | – |
 Foundayo | Listed, no rate given | – | – | – |
 Saxenda | Listed, no rate given | – | – | – |
| Ozempic | Not listed | – | – | – |
 Rybelsus | Not listed | – | – | – |
 Mounjaro | Not listed | – | – | – |
 Trulicity | Not listed | – | – | – |
 Victoza | Not listed | – | – | – |
| Byetta | Not listed | – | – | – |
Source: Zepbound label (DailyMed).
Source: FDA label (DailyMed).