Ozempic Dry Mouth, Metallic Taste, Mouth Sores: Causes
The Ozempic label does not list dry mouth as a side effect. What people mean by it: a mouth that feels dry or sticky.
- In the label
- Not listed
- Most common in the label
- Nausea 20.3%
Ozempic in short
Its half-life is about 1 week. After 7 d, half is gone, and about 3% is left once five half-lives pass (35 d).
In SUSTAIN 1, which lasted 30 weeks, people with type 2 diabetes lost 4.7 kg, compared with 1.2 kg on placebo.
Monthly prices in US dollars: the list price and self-pay offers, both taken from the maker's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.
What the Ozempic label lists instead
The Ozempic label does not list dry mouth. These are the five side effects listed most often.
| Side effect | Placebo | Ozempic 0.5 mg | Ozempic 1 mg | More than placebo, 1 mg |
|---|---|---|---|---|
| Nausea | 6.1% | 15.8% | 20.3% | +14.2 points |
| Vomiting | 2.3% | 5% | 9.2% | +6.9 points |
| Diarrhea | 1.9% | 8.5% | 8.8% | +6.9 points |
| Abdominal pain | 4.6% | 7.3% | 5.7% | +1.1 points |
| Constipation | 1.5% | 5% | 3.1% | +1.6 points |
Source: Ozempic label (DailyMed).
Comparing dry mouth with Ozempic and other GLP-1s
Labels draw on separate trials that involved different groups of people. Use it as a rough guide.
| Medicine | Highest rate in the label | Dose group | Placebo | People in the trials |
|---|---|---|---|---|
 Saxenda | 2.3% | all doses | 1% | Adults with obesity or overweight (weight management) |
 Zepbound | Listed, no rate given | – | – | – |
| Ozempic | Not listed | – | – | – |
 Wegovy | Not listed | – | – | – |
 Rybelsus | Not listed | – | – | – |
 Mounjaro | Not listed | – | – | – |
 Foundayo | Not listed | – | – | – |
 Trulicity | Not listed | – | – | – |
 Victoza | Not listed | – | – | – |
| Byetta | Not listed | – | – | – |
Source: Saxenda label (DailyMed).
Source: FDA label on DailyMed.