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GLP-1 Decoder

Ozempic Dizziness: How Common, How Long It Lasts, What Helps

The Ozempic label names dizziness as a reported side effect but gives no trial rate for it.

In the label
Listed, no rate given
Label term
dizziness

A quick look at Ozempic

How long the drug remains in the body
100%50%25%0%07 d14 d21 d28 d35 d50%25%12.5%time after the dose

Its half-life is about 1 week: after 7 d, half is gone, and about 3% remains after five half-lives (35 d).

Weight loss during the main trial
Ozempic (SUSTAIN 1)4.7 kgPlacebo1.2 kg

In SUSTAIN 1, people with type 2 diabetes lost 4.7 kg over 30 weeks, compared with 1.2 kg on placebo.

Costs over time
202520262027$1,027.51$0List priceSelf-pay

Monthly prices in US dollars include the list price and self-pay offers, with each amount taken from the maker's price page.

Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.

What the Ozempic label lists instead

The Ozempic label does not give a rate for dizziness. The five side effects it names most often are set out below, each with a rate.

Table 1. Placebo-Controlled Trials Reported Adverse Reactions in ≥5% of OZEMPIC-Treated Patients with Type 2 Diabetes Mellitus
Side effectPlaceboOzempic 0.5 mgOzempic 1 mgMore than placebo, 1 mg
Nausea6.1%15.8%20.3%+14.2 points
Vomiting2.3%5%9.2%+6.9 points
Diarrhea1.9%8.5%8.8%+6.9 points
Abdominal pain4.6%7.3%5.7%+1.1 points
Constipation1.5%5%3.1%+1.6 points

Taken from the Ozempic label (DailyMed).

How Ozempic compares with other GLP-1s on Dizziness

Each label covers its own trials, and those trials used different groups of people. Consider it a rough guide.

Dizziness across GLP-1 labels
MedicineHighest rate in the labelDose groupPlaceboPeople in the trials
Byetta9%all doses6%Adults with type 2 diabetes
Wegovy8%2.4 mg4%Adults with obesity or overweight (weight management)
Saxenda6.9%all doses5%Adults with obesity or overweight (weight management)
Zepbound5%10 mg2%Adults with obesity or overweight (weight management)
OzempicListed, no rate given–––
FoundayoListed, no rate given–––
RybelsusNot listed–––
MounjaroNot listed–––
TrulicityNot listed–––
VictozaNot listed–––

Taken from the Wegovy label (DailyMed), Zepbound label (DailyMed), Saxenda label (DailyMed), and Byetta label (DailyMed).

Source: FDA label (DailyMed).

What the Ozempic label says

Dizziness, taken straight from the label, word for word:

“Other adverse reactions with a frequency of >0.4% were associated with OZEMPIC include fatigue, dysgeusia and dizziness.”

Source: FDA label (DailyMed).