Skip to content
GLP-1 Decoder

Liraglutide Sulfur Burps: How Common, How Long It Lasts

Yes. Sulfur burps is listed in the Saxenda label at 4.5% on Saxenda. Placebo in the Saxenda trials: 0.2%. Smaller, slower meals help most.

Labels that list it
1 of 2
Highest rate
4.5% Saxenda

A quick look at Saxenda

How long it remains in the body
100%50%25%0%013 h26 h39 h2.2 d2.7 d50%25%12.5%time after the dose

Its half-life is about 13 hours: after 13 h, half is gone, and after five half-lives (2.7 d), about 3% remains.

The amount of weight lost in its main trial
Saxenda (SCALE Obesity and Prediabetes)7.4%Placebo3%

For Obesity and Prediabetes, 56 weeks, SCALE recorded 7.4% of body weight, versus 3% on placebo.

Sources: FDA label (DailyMed).

How often it appears with liraglutide compared with placebo

Liraglutide sulfur burps are listed by dose group in label trials. Within that same trial, the placebo group serves as the comparison group.

Sulfur burps listed in liraglutide labels
Medicine and doseSulfur burpsPlaceboMore than placeboPeople in the trials
Saxenda Saxenda4.5%0.2%+4.3 pointsAdults with obesity, or who are overweight (weight management)

Reference: Saxenda label (DailyMed).

Sulfur burps: liraglutide and other GLP-1s compared

Different groups of people took part in the trials. Treat it as a rough guide.

The table also lists the pill forms: Foundayo.

Sulfur burps across GLP-1 labels
MedicineHighest rate in the labelDose groupPlaceboPeople in the trials
Foundayo8%9 mg1%Adults with obesity or overweight (weight management)
Wegovy7%2.4 mgNot reportedAdults with obesity or overweight (weight management)
Zepbound5%10 mg1%Adults with obesity or overweight (weight management)
Saxenda4.5%all doses0.2%Adults with obesity or overweight (weight management)
OzempicNot by this name–––
RybelsusNot by this name–––
MounjaroNot by this name–––
TrulicityNot by this name–––
VictozaNot listed–––
ByettaNot by this name–––

Sources: Wegovy label (DailyMed), Zepbound label (DailyMed), Foundayo label (DailyMed), Saxenda label (DailyMed).

Reference: FDA label (DailyMed).

Why it happens on liraglutide

These medicines make your stomach empty more slowly. Sulfur burps can happen when food stays longer, especially after large or fatty meals.

Source: health.clevelandclinic.org.

What helps, step by step

  1. Reduce sugary and highly processed foods.
  2. Right after you take a dose, limit high-fiber foods.
  3. Stop eating when you feel full, and choose smaller meals. These medicines slow down how fast your stomach empties.
  4. Eat slowly. Your brain needs time to notice when you feel full.
  5. Symptoms are often brought on by fatty, greasy, and sugary foods. Eat them in moderation.
  6. If the problem does not improve, let your prescriber know. Another GLP-1 may be suggested, or dose increases may be slowed.

Check anything from the drugstore with the interactions checker for GLP-1 before taking it.

Source: health.clevelandclinic.org.