Victoza Fatigue: How Common, How Long It Lasts, What Helps
Fatigue is not listed on the Victoza label as a side effect. What people mean by it: feeling tired or low on energy. Labels also use the word asthenia (weakness).
- In the label
- Not listed
- Most common in the label
- Nausea 20%
Victoza: a quick overview
Its half-life is about 13 hours. After 13 h, half is gone, and about 3% remains after five half-lives (2.7 d).
In the 52-week LEAD-3 trial involving type 2 diabetes, people lost 2.5 kg, compared with 1.1 kg on placebo.
Sources: FDA label (DailyMed).
What is listed on the Victoza label instead?
Fatigue is not listed on the Victoza label. Fatigue is not listed on the Victoza label. It names these five side effects most often.
| Side effect | Placebo | Victoza 1.2 mg | Victoza 1.8 mg | More than placebo, 1.8 mg |
|---|---|---|---|---|
| Nausea | 5% | 18% | 20% | +15 points |
| Diarrhea | 4% | 10% | 12% | +8 points |
| Headache | 7% | 11% | 10% | +3 points |
| Nasopharyngitis | 8% | 9% | 10% | +2 points |
| Decreased appetite | 1% | 10% | 9% | +8 points |
Source: Victoza label (DailyMed).
Victoza Fatigue: how it compares with other GLP-1s
Each label covers its own trials, and those trials included different groups of people. Treat this as a rough guide. As a rough guide, use it.
The pill forms in the table include Foundayo.
| Medicine | Highest rate in the label | Dose group | Placebo | People in the trials |
|---|---|---|---|---|
 Wegovy | 11% | 2.4 mg | 5% | Adults with obesity or overweight (weight management) |
 Foundayo | 9% | 17.2 mg | 4% | Adults with obesity or overweight (weight management) |
 Saxenda | 7.5% | all doses | 4.6% | Adults with obesity or overweight (weight management) |
 Zepbound | 7% | 15 mg | 3% | Adults with obesity or overweight (weight management) |
 Trulicity | 5.6% | 1.5 mg | 2.6% | Adults with type 2 diabetes |
| Byetta | 4% | all doses | 2% | Adults with type 2 diabetes |
 Ozempic | Listed, no rate given | – | – | – |
 Mounjaro | Listed, no rate given | – | – | – |
 Rybelsus | Not listed | – | – | – |
| Victoza | Not listed | – | – | – |
Sources: Wegovy label (DailyMed), Zepbound label (DailyMed), Foundayo label (DailyMed), Trulicity label (DailyMed), Saxenda label (DailyMed), Byetta label (DailyMed).
Source for this information: FDA label (DailyMed).