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GLP-1 Decoder

Victoza Face: How Common, How Long It Lasts, What Helps

The Victoza label does not list face changes as a side effect. What people mean by it: a thinner or older-looking face after fast weight loss (often called Ozempic face).

In the label
Not listed
Most common in the label
Nausea 20%

Victoza: key facts

How long it remains in the body
100%50%25%0%013 h26 h39 h2.2 d2.7 d50%25%12.5%time after the dose

Its half-life is about 13 hours: after 13 h, half remains, while about 3% remains after five half-lives (2.7 d).

Main trial weight loss
Victoza (LEAD-3)2.5 kgPlacebo1.1 kg

In LEAD-3, people with type 2 diabetes lost 2.5 kg over 52 weeks, compared with 1.1 kg on placebo.

Sources: FDA label (DailyMed).

The Victoza label lists these instead:

The Victoza label does not list face changes. These five side effects are listed most often on the label.

Table 1. Reported adverse reactions affected ≥5% of Adult Patients Treated with VICTOZA for Type 2 Diabetes Mellitus
Side effectPlaceboVictoza 1.2 mgVictoza 1.8 mgMore than placebo, 1.8 mg
Nausea5%18%20%+15 points
Diarrhea4%10%12%+8 points
Headache7%11%10%+3 points
Nasopharyngitis8%9%10%+2 points
Decreased appetite1%10%9%+8 points

Source: Victoza label (DailyMed).

Source: FDA DailyMed label.