Skip to content
GLP-1 Decoder

Ozempic vs Victoza: Weight Loss, Side Effects, Price

Ozempic (semaglutide) and Victoza (liraglutide) are both GLP-1 medicines, weekly injection versus daily injection. Ozempic self-pay starts at $199 per month.

A quick look at Ozempic and Victoza

Time for the drug level to drop by half (days)
Ozempic (about 1 week)7 dVictoza (about 13 hours)0.5 d
Weight lost in the main trial
Ozempic (SUSTAIN 1)4.7 kgVictoza (LEAD-3)2.5 kg

Sources: 1 2, based on the FDA label (DailyMed)

Ozempic and Victoza compared side by side

Ozempic and Victoza compared side by side
OzempicVictoza
Medicine Ozempic Victoza
Active ingredientsemaglutideliraglutide
ManufacturerNovo NordiskNovo Nordisk
How it is takenWeekly injectionDaily injection
Approved forHeart risk and type 2 diabetes, along with kidney disease affecting people with type 2 diabetesType 2 diabetes and heart risk
First FDA approval20172010
Most common side effectNausea 20.3% vs 6.1% on placeboNausea 20% vs 5% on placebo
List price$1,027.51 per pen$543.51 per 2 pens
Self-pay from$199 per monthNot listed
FDA shortageResolved February 21, 2025On the FDA shortage list

Sources: FDA label, FDA label (DailyMed), Novo Nordisk pricing, TrumpRx.

The side effects compared

Each label tested the people taking it against the placebo group from that same study. Compare each drug with its own placebo first.

Labels show side effects for Ozempic and Victoza at the highest dose
Side effectOzempicPlacebo (Ozempic trials)VictozaPlacebo (Victoza trials)
Nausea20.3%6.1%20%5%
Vomiting9.2%2.3%9%2%
Diarrhea8.8%1.9%12%4%
Abdominal pain7.3%4.6%Not listedNot listed
Constipation5%1.5%Not listedNot listed
HeadacheNot listedNot listed11%7%
NasopharyngitisNot listedNot listed10%8%
Decreased appetiteNot listedNot listed10%1%
DyspepsiaNot listedNot listed7%1%
Upper Respiratory Tract InfectionNot listedNot listed7%6%

Sources: 1 2, based on the FDA label (DailyMed)

Price and coverage compared

Prices by route, shown before and after savings
MedicineHow you payPrice
OzempicList price before insurance$1,027.51 per pen
OzempicOzempic Savings Offer (insured)the offer starts at $25 each month. It lasts for up to 3 months
OzempicSelf-pay: Ozempic pill (from 1.5 mg)$149 per month
OzempicSelf-pay: Ozempic pen introductory offer for doses (0.25 mg, 0.5 mg), covering the first 2 fills$199 per month
OzempicSelf-pay: Ozempic pen at 0.25 mg, 0.5 mg, or 1 mg$349 per month
OzempicSelf-pay: Ozempic pen 2 mg$499 per month
OzempicSelf-pay via TrumpRx$199 per month
VictozaList price before insurance$543.51 per 2 pens

In November 2026, prices were checked using 1 2 Novo Nordisk pricing, NovoCare, TrumpRx.

Who should pick which?

Your prescriber reviews your health history, other medicines, and coverage.