Victoza for Pregnancy: Evidence, Eligibility, Coverage
The Victoza label: Only use it during pregnancy if the benefit justifies the possible risk to the baby.
- Active ingredient
- liraglutide
- How it is taken
- daily injection
A quick overview of Victoza
Its half-life is about 13 hours. By 13 h, half is gone. At five half-lives (2.7 d), about 3% remains.
In LEAD-3, over 52 weeks with type 2 diabetes, people lost 2.5 kg, compared with 1.1 kg on placebo.
Sources: FDA label on DailyMed.
What the Victoza label says about Pregnancy
| Medicine | What the label says |
|---|---|
| Only use it during pregnancy if the benefit justifies the possible risk to the baby. |
Taken from the FDA labels: FDA label on DailyMed.
Label warnings: FDA label on DailyMed.
Each GLP-1 label on pregnancy
| Medicine | What the label says | How it is taken |
|---|---|---|
| Only use it during pregnancy if the benefit justifies the possible risk to the baby. | daily injection | |
| If you plan a pregnancy, stop at least 2 months ahead; pregnancy data are limited. | weekly injection | |
| During pregnancy, weight loss gives no benefit and may harm the baby. Stop the medicine once you are pregnant. Also stop it at least 2 months before you try to conceive. | weekly injection or daily tablet | |
| If you plan a pregnancy, stop at least 2 months ahead; pregnancy data are limited. | daily tablet | |
| There is not enough data in pregnancy to judge the risk, so talk to your doctor before you try to conceive. | weekly injection | |
| During pregnancy, weight loss does not help and may harm the baby. Once a pregnancy is recognized, stop the medicine. | weekly injection | |
| During pregnancy, weight loss does not help and may harm the baby. Once a pregnancy is recognized, stop the medicine and use effective birth control while taking it. | daily tablet | |
| There is not enough data in pregnancy to judge the risk, so talk to your doctor before you try to conceive. | weekly injection | |
| You gain no benefit from losing weight in pregnancy. Research in animals points to a possible risk to the baby. | daily injection | |
| Byetta | There is not enough data in pregnancy to judge the risk, so talk to your doctor before you try to conceive. | twice-daily injection |
Sources: FDA label on DailyMed.
Questions to ask your prescriber
- How far ahead of trying to conceive should I stop?
- What should I do if I become pregnant while taking it?
On DailyMed, read the full Victoza prescribing information.