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GLP-1 Decoder

Victoza for Teens: Evidence, Eligibility, Coverage

Yes, from age 10: Victoza is FDA approved for type 2 diabetes in children 10 and older.

For teens
From age 10, for type 2 diabetes
Active ingredient
liraglutide
How it is taken
daily injection

A quick look at Victoza

Time it stays in the body
100%50%25%0%013 h26 h39 h2.2 d2.7 d50%25%12.5%time after the dose

Its half-life is about 13 hours. At five half-lives (2.7 d), about 3% remains; half of it is gone after 13 h.

Main trial: amount of weight lost
Victoza (LEAD-3)2.5 kgPlacebo1.1 kg

LEAD-3, 52 weeks: people with type 2 diabetes lost 2.5 kg, compared with 1.1 kg on placebo.

Sources: FDA label (DailyMed).

Who qualifies?

Victoza: who qualifies
SourceWho qualifies
FDA labelThis medicine, used with diet and exercise, lowers blood sugar in people ages 10 and older who have type 2 diabetes.
FDA labelFor adults with heart disease and type 2 diabetes, it lowers the risk of heart attack, stroke, or death linked to the heart.

Sources: FDA label (DailyMed).

What is different for teens?

Victoza: label points for teens
What changesWhat the label says
Acute PancreatitisCan cause inflammation of the pancreas. Seek medical care if your stomach pain is severe, will not go away, and sometimes reaches your back.
Acute Gallbladder DiseaseGallstones and gallbladder inflammation can happen. Report upper-right belly pain, fever, or yellow skin or eyes.

Taken from the FDA labels: FDA label (DailyMed).

These warnings come from the label at DailyMed: FDA label.

Coverage for teens

Alternatives for teens

GLP-1 medicines and teens
MedicineFor teensHow it is takenTrial result
VictozaFrom age 10, for type 2 diabetesdaily injectionNot listed
WegovyFrom age 12, for weight lossweekly injection or daily tablet16.1% drop in BMI
MounjaroFrom age 10, for type 2 diabetesweekly injectionNot listed
TrulicityFrom age 10, for type 2 diabetesweekly injectionNot listed
SaxendaFrom age 12, for weight lossdaily injectionNot listed
OzempicAdults onlyweekly injectionNot listed
RybelsusAdults onlydaily tabletNot listed
ZepboundAdults onlyweekly injectionNot listed
FoundayoAdults onlydaily tabletNot listed
ByettaAdults onlytwice-daily injectionNot listed

Sources: FDA label (DailyMed), PubMed.

What to ask your prescriber

See the Victoza label on DailyMed for the complete prescribing information.