Skip to content
GLP-1 Decoder

Victoza for Fatty Liver: Evidence, Eligibility, Coverage

Victoza is not FDA approved for fatty liver disease (MASH). It is approved for type 2 diabetes and heart risk.

For fatty liver disease (MASH)
Not an approved use
Active ingredient
liraglutide
How it is taken
daily injection

Victoza: a quick look

How long it remains in the body
100%50%25%0%013 h26 h39 h2.2 d2.7 d50%25%12.5%time after the dose

About 13 hours is the half-life. Half is gone after 13 h, while five half-lives (2.7 d) leave about 3%.

Main trial weight loss
Victoza (LEAD-3)2.5 kgPlacebo1.1 kg

In the 52-week LEAD-3 trial of type 2 diabetes, people lost 2.5 kg compared with 1.1 kg on placebo.

Sources: FDA label (DailyMed).

Who qualifies?

Who qualifies to use Victoza
SourceWho qualifies
FDA labelWith diet and exercise, this medicine lowers blood sugar in adults and in children aged 10 and older with type 2 diabetes.
FDA labelAmong adults with both type 2 diabetes and heart disease, it lowers the risk of heart attack, stroke, or heart-related death.

Sources: FDA label (DailyMed).

For fatty liver, what changes?

Victoza: fatty liver disease (MASH) points from the label
What changesWhat the label says
Acute PancreatitisCan cause inflammation of the pancreas. Stop taking it and get care if severe stomach pain continues and sometimes spreads to the back.
Acute Gallbladder DiseaseGallstones and gallbladder inflammation can happen. Report pain in the upper right area of your belly, fever, or yellow skin or eyes.

The source of these points is the FDA labels: FDA DailyMed.

The label lists these warnings: FDA DailyMed label.

Coverage for fatty liver

Part D plans may provide coverage for a GLP-1 for fatty liver disease, for moderate to severe sleep apnea, or for type 2 diabetes.

The source listed here: medicare.gov.

Other fatty liver options

GLP-1 medicines and fatty liver disease (MASH)
MedicineFor fatty liver disease (MASH)How it is takenTrial result
WegovyFDA approvedweekly injection or daily tablet62.9% mASH resolved without worse scarring
VictozaNot an approved usedaily injectionNot listed
OzempicNot an approved useweekly injectionNot listed
RybelsusNot an approved usedaily tabletNot listed
MounjaroNot an approved useweekly injectionNot listed
ZepboundNot an approved useweekly injectionNot listed
FoundayoNot an approved usedaily tabletNot listed
TrulicityNot an approved useweekly injectionNot listed
SaxendaNot an approved usedaily injectionNot listed
ByettaNot an approved usetwice-daily injectionNot listed

Sources listed: FDA DailyMed label, PubMed.

Ask your prescriber these questions

Please read the entire Victoza prescribing information on DailyMed.