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GLP-1 Decoder

Saxenda Butt: How Common, How Long It Lasts, What Helps

The Saxenda label does not include Butt changes as a side effect. What people mean by it: a flatter or saggier buttock area after fast weight loss.

In the label
Not listed
Most common in the label
Nausea 39.3%

Saxenda in brief

How long it remains in your body
100%50%25%0%013 h26 h39 h2.2 d2.7 d50%25%12.5%time after the dose

Its half-life is about 13 hours. At 13 h, half has gone; by five half-lives (2.7 d), about 3% remains.

What the main trial found about weight loss
Saxenda (SCALE Obesity and Prediabetes)7.4%Placebo3%

For SCALE Obesity and Prediabetes, 56 weeks, the figure for body weight was 7.4%, compared with 3% on placebo.

Sources: FDA label (DailyMed).

What the Saxenda label lists instead

The Saxenda label does not include Butt changes. The label lists these five side effects most often.

Table 2. Adverse Reactions Occurring in ≥2% and More Frequently than Placebo among SAXENDA-treated Adult Patients
Side effectPlaceboSaxenda SaxendaMore than placebo
Nausea13.8%39.3%+25.5 points
Diarrhea9.9%20.9%+11 points
Constipation8.5%19.4%+10.9 points
Vomiting3.9%15.7%+11.8 points
Injection Site Reaction10.5%13.9%+3.4 points

Source: Saxenda label (DailyMed).

Source: FDA label (DailyMed).