Mounjaro Headache: How Common, How Long It Lasts, What Helps
Headache does not appear on the Mounjaro label as a side effect. What people mean by it: pain in the head.
- In the label
- Not listed
- Most common in the label
- Nausea 18%
Mounjaro: a quick overview
About 5 days for the half-life: after 5 d, half is gone, while five half-lives (25 d) leave about 3%.
SURPASS-1, 40 weeks, type 2 diabetes: participants lost 7.8 kg, compared with 1 kg on placebo.
Monthly price points in US dollars show the list price and self-pay offers, all read from the maker's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, pricinginfo.lilly.com.
What the Mounjaro label lists instead
Headache does not appear on the Mounjaro label. The five side effects listed most often are these.
| Side effect | Placebo | Mounjaro 5 mg | Mounjaro 10 mg | Mounjaro 15 mg | More than placebo, 15 mg |
|---|---|---|---|---|---|
| Nausea | 4% | 12% | 15% | 18% | +14 points |
| Diarrhea | 9% | 12% | 13% | 17% | +8 points |
| Decreased Appetite | 1% | 5% | 10% | 11% | +10 points |
| Vomiting | 2% | 5% | 5% | 9% | +7 points |
| Dyspepsia | 3% | 8% | 8% | 5% | +2 points |
Source: Mounjaro label (DailyMed).
Comparing Headache on Mounjaro with other GLP-1s
The label for each drug covers its own trials, and those studies used different groups of people. Use the information as a rough guide.
The pill form shown in the table is Foundayo.
| Medicine | Highest rate in the label | Dose group | Placebo | People in the trials |
|---|---|---|---|---|
 Wegovy | 14% | 2.4 mg | 10% | Adults with obesity or overweight (weight management) |
 Saxenda | 13.6% | all doses | 12.6% | Adults with obesity or overweight (weight management) |
 Victoza | 11% | 1.2 mg | 7% | Adults with type 2 diabetes |
 Foundayo | 9% | 9 mg | 7% | Adults with obesity or overweight (weight management) |
| Byetta | 9% | all doses | 6% | Adults with type 2 diabetes |
 Ozempic | Not listed | – | – | – |
 Rybelsus | Not listed | – | – | – |
| Mounjaro | Not listed | – | – | – |
 Zepbound | Not listed | – | – | – |
 Trulicity | Not listed | – | – | – |
Sources: Wegovy label (DailyMed), Foundayo label (DailyMed), Saxenda label (DailyMed), Victoza label (DailyMed), Byetta label (DailyMed).
Source: FDA label (DailyMed).