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GLP-1 Decoder

GLP-1 Face: Why It Happens, Who Gets It, Can It Reverse?

The GLP-1 medicines labels do not list face changes as a side effect. What people mean by it: a thinner or older-looking face after fast weight loss (often called Ozempic face).

In the label
Not listed
Most common in the label
Nausea 20.3%

Source: FDA DailyMed label.

Half-life and weight loss overview

How long each one remains in the body
Wegovy7 dOzempic7 dRybelsus7 dZepbound5.5 dMounjaro5 dTrulicity5 dFoundayo1.6 dSaxenda0.5 dVictoza0.5 dByetta0.1 d

Half-life in days shows how long the body needs to clear half a dose. This comes from section 12.3 in each FDA label.

Weight loss in each medicine's main weight trial
Zepbound20.9%Wegovy14.9%Foundayo11.1%Saxenda7.4%

A percentage of body weight Trials vary in their doses and lengths. On the relevant page, compare each result with the placebo used in that trial.

Sources (10)

The FDA label (DailyMed): 1 2 3 4 5 6 7 8 9 10.