Wegovy and Pregnancy: When to Stop, Fertility, the Data
The Wegovy label: Stop taking it if you are pregnant, and also at least 2 months before you plan to conceive. Weight loss in pregnancy may harm the baby and offers no benefit.
- Active ingredient
- semaglutide
- How it is taken
- weekly injection or daily tablet
Wegovy key facts
Its half-life is about 1 week: after 7 d, half is gone, and about 3% remains after five half-lives (35 d).
STEP 1 over 68 weeks: 14.9% of body weight, compared with 2.4% on placebo.
Monthly prices in US dollars include the list price and self-pay offers, each taken from the maker's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.
Pregnancy information in the Wegovy label
| Medicine | What the label says |
|---|---|
| Wegovy | Stop taking it if you are pregnant, and also at least 2 months before you plan to conceive. Weight loss in pregnancy may harm the baby and offers no benefit. |
Taken from FDA labels: FDA label (DailyMed).
The label warnings are the source: FDA label (DailyMed).
Each GLP-1 label on pregnancy
| Medicine | What the label says | How it is taken |
|---|---|---|
| Wegovy | Stop taking it if you are pregnant, and also at least 2 months before you plan to conceive. Weight loss in pregnancy may harm the baby and offers no benefit. | weekly injection or daily tablet |
 Ozempic | If you plan a pregnancy, stop the medicine at least 2 months ahead of it; pregnancy data are limited. | weekly injection |
 Rybelsus | If you plan a pregnancy, stop the medicine at least 2 months ahead of it; pregnancy data are limited. | daily tablet |
 Mounjaro | Talk to your doctor before you try to conceive; the data gathered in pregnancy are too limited to tell how risky it is. | weekly injection |
 Zepbound | Weight loss in pregnancy does no good and may harm the baby. Stop taking it once a pregnancy is recognized. | weekly injection |
 Foundayo | Weight loss in pregnancy does no good and may harm the baby. Stop taking it once a pregnancy is recognized and use effective birth control while taking it. | daily tablet |
 Trulicity | Talk to your doctor before you try to conceive; the data gathered in pregnancy are too limited to tell how risky it is. | weekly injection |
 Saxenda | Weight loss during pregnancy gives no benefit. Studies in animals suggest the baby could face some risk. | daily injection |
 Victoza | Use it during pregnancy only if the benefit justifies any risk the baby could face. | daily injection |
| Byetta | Talk to your doctor before you try to conceive; the data gathered in pregnancy are too limited to tell how risky it is. | twice-daily injection |
Source details: FDA label (DailyMed).
Questions to ask your prescriber
- How far in advance of trying to conceive should I stop taking it?
- If I become pregnant while on this medicine, what should I do next?
Read Wegovy information on DailyMed for the complete prescribing details.