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GLP-1 Decoder

Wegovy for Breastfeeding: Evidence, Eligibility, Coverage

The Wegovy label on breastfeeding: The tablets contain SNAC, and breast milk contains it; for the injection, it is unknown whether it passes into breast milk.

Active ingredient
semaglutide
How it is taken
weekly injection or daily tablet

Wegovy in brief

How long it remains in the body
100%50%25%0%07 d14 d21 d28 d35 d50%25%12.5%time after the dose

Its half-life is about 1 week: after 7 d, half is gone, and after five half-lives (35 d) about 3% is left.

Weight loss in the main trial
Wegovy (STEP 1)14.9%Placebo2.4%

STEP 1 ran 68 weeks: 14.9% of body weight, compared with 2.4% on placebo.

What it costs over time
202520262027$1,349.02$0List priceSelf-pay

In US dollars, monthly prices include the list price and self-pay offers, and each one comes from the maker's price page.

Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.

What the label says on breastfeeding

How the Wegovy label treats breastfeeding
MedicineWhat the label says
WegovyThe tablets contain SNAC, and breast milk contains it; for the injection, it is unknown whether it passes into breast milk.

These labels come from the FDA: FDA label on DailyMed.

These warnings come from the label: FDA label on DailyMed.

Each GLP-1 label on breastfeeding

GLP-1 medicines and breastfeeding
MedicineWhat the label saysHow it is taken
WegovyThe tablets contain SNAC, and breast milk contains it; for the injection, it is unknown whether it passes into breast milk.weekly injection or daily tablet
OzempicIt is not known whether it passes into human breast milk.weekly injection
RybelsusThe tablets contain SNAC, and breast milk contains it.daily tablet
MounjaroIn one small study, levels in breast milk were undetectable or low.weekly injection
ZepboundIn one small study, levels in breast milk were undetectable or low.weekly injection
FoundayoIt is not known whether it passes into human breast milk.daily tablet
TrulicityIt is not known whether it passes into human breast milk.weekly injection
SaxendaIt is not known whether it passes into human breast milk.daily injection
VictozaIt is not known whether it passes into human breast milk.daily injection
ByettaIt is not known whether it passes into human breast milk.twice-daily injection

Sources: FDA label (DailyMed).

Questions to ask your prescriber

For the full details, see the Wegovy prescribing details on DailyMed.