Liraglutide for Pregnancy: Evidence, Eligibility, Coverage
The Liraglutide label: In pregnancy, use it only if the benefit is enough to justify the risk that may be involved for the baby.
- Brands
- Victoza and Saxenda
Saxenda: key facts
The half-life is about 13 hours: after 13 h, half is gone, and after five half-lives (2.7 d), about 3% remains.
SCALE Obesity and Prediabetes, 56 weeks: the figure was 7.4% of body weight, compared with 3% for placebo.
Sources: FDA label (DailyMed).
What the label says about Pregnancy
| Medicine | What the label says |
|---|---|
 Victoza | In pregnancy, use it only if the benefit is enough to justify the risk that may be involved for the baby. |
 Saxenda | During pregnancy, losing weight offers no benefit, and studies in animals point to a possible risk for the baby. |
The label includes these warnings: FDA DailyMed.
Each GLP-1 label on pregnancy
| Medicine | What the label says | How it is taken |
|---|---|---|
| Saxenda | During pregnancy, losing weight offers no benefit, and studies in animals point to a possible risk for the baby. | daily injection |
| Victoza | In pregnancy, use it only if the benefit is enough to justify the risk that may be involved for the baby. | daily injection |
 Ozempic | Pregnancy data are limited. For a planned pregnancy, stop this medicine at least 2 months beforehand. | weekly injection |
 Wegovy | In pregnancy, weight loss gives no benefit and may harm the baby. Stop it when pregnant and no less than 2 months before trying to conceive. | weekly injection or daily tablet |
 Rybelsus | Pregnancy data are limited. For a planned pregnancy, stop this medicine at least 2 months beforehand. | daily tablet |
 Mounjaro | Pregnancy data are too limited to judge the risk; speak with your doctor before trying to conceive. | weekly injection |
 Zepbound | Weight loss during pregnancy offers no benefit. It may harm the baby. Stop it as soon as a pregnancy is recognized. | weekly injection |
 Foundayo | Weight loss during pregnancy offers no benefit. It may harm the baby. Stop it as soon as a pregnancy is recognized and use effective birth control while taking it. | daily tablet |
 Trulicity | Pregnancy data are too limited to judge the risk; speak with your doctor before trying to conceive. | weekly injection |
| Byetta | Pregnancy data are too limited to judge the risk; speak with your doctor before trying to conceive. | twice-daily injection |
Sources: FDA label (DailyMed).
Ask your prescriber these questions
- When should I stop taking it before trying to conceive?
- If I get pregnant while taking it, what should I do?