Saxenda for Pregnancy: Evidence, Eligibility, Coverage
The Saxenda label: While pregnant, losing weight offers no benefit; animal studies raise the possibility of harm to the baby.
- Active ingredient
- liraglutide
- How it is taken
- daily injection
Saxenda in brief
Half-life about 13 hours: after 13 h half is gone, and about 3% remains after five half-lives (2.7 d).
In the SCALE Obesity and Prediabetes, 56 weeks trial, weight loss reached 7.4% of body weight, while the placebo group reached 3%.
Sources: FDA label (DailyMed).
What the Saxenda label says about Pregnancy
| Medicine | What the label says |
|---|---|
| Saxenda | While pregnant, losing weight offers no benefit; animal studies raise the possibility of harm to the baby. |
Labels from FDA: FDA DailyMed label.
Warnings source: FDA DailyMed label
Each GLP-1 label on pregnancy
| Medicine | What the label says | How it is taken |
|---|---|---|
| Saxenda | While pregnant, losing weight offers no benefit; animal studies raise the possibility of harm to the baby. | daily injection |
 Ozempic | If you are planning a pregnancy, stop the medicine at least 2 months ahead; data on pregnancy remain limited. | weekly injection |
 Wegovy | Weight loss during pregnancy brings no benefit and may harm the baby, so stop when you are pregnant and stop at least 2 months before you try to conceive. | weekly injection or daily tablet |
 Rybelsus | If you are planning a pregnancy, stop the medicine at least 2 months ahead; data on pregnancy remain limited. | daily tablet |
 Mounjaro | For Pregnancy, the data are too limited to work out the risk. Talk with your doctor before you try to conceive. | weekly injection |
 Zepbound | During pregnancy, losing weight gives no benefit and may also harm the baby. | weekly injection |
 Foundayo | During pregnancy, losing weight gives no benefit and may also harm the baby and use effective birth control while taking it. | daily tablet |
 Trulicity | For Pregnancy, the data are too limited to work out the risk. Talk with your doctor before you try to conceive. | weekly injection |
 Victoza | During pregnancy, use it only if the benefit is enough to justify any possible risk for the baby. | daily injection |
| Byetta | For Pregnancy, the data are too limited to work out the risk. Talk with your doctor before you try to conceive. | twice-daily injection |
Sources: FDA label (DailyMed).
Questions to ask your prescriber
- When should I stop taking it before trying to conceive?
- What should I do if I become pregnant while taking it?
For the complete prescribing details, read Saxenda on DailyMed.