Ozempic and Pregnancy: When to Stop, Risks, 'Ozempic Babies'
The Ozempic label: Before a planned pregnancy, stop taking it at least 2 months ahead; pregnancy data are limited.
- Active ingredient
- semaglutide
- How it is taken
- weekly injection
Ozempic in brief
Its half-life is about 1 week: after 7 d, half is gone, and after five half-lives (35 d), about 3% remains.
In SUSTAIN 1, people with type 2 diabetes lost 4.7 kg over 30 weeks, compared with 1.2 kg on placebo.
Prices each month in US dollars include the list price and self-pay offers, all read from the maker's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.
The label on pregnancy: what it says
| Medicine | What the label says |
|---|---|
| Ozempic | Before a planned pregnancy, stop taking it at least 2 months ahead; pregnancy data are limited. |
From FDA labels: DailyMed label.
These warnings come from the DailyMed FDA label.
Each GLP-1 label on pregnancy
| Medicine | What the label says | How it is taken |
|---|---|---|
| Ozempic | Before a planned pregnancy, stop taking it at least 2 months ahead; pregnancy data are limited. | weekly injection |
 Wegovy | Weight loss during pregnancy is not helpful and may harm the baby; stop the medicine once you are pregnant and at least 2 months ahead of trying to conceive. | weekly injection or daily tablet |
 Rybelsus | Before a planned pregnancy, stop taking it at least 2 months ahead; pregnancy data are limited. | daily tablet |
 Mounjaro | There is not enough Pregnancy data to determine the risk; ask your doctor about it before you try to conceive. | weekly injection |
 Zepbound | Losing weight in pregnancy does no good and may harm the baby; stop it as soon as a pregnancy is recognized. | weekly injection |
 Foundayo | Losing weight in pregnancy does no good and may harm the baby; stop it as soon as a pregnancy is recognized and use effective birth control while taking it. | daily tablet |
 Trulicity | There is not enough Pregnancy data to determine the risk; ask your doctor about it before you try to conceive. | weekly injection |
 Saxenda | In pregnancy, weight loss gives no benefit; animal studies point to a possible risk for the baby. | daily injection |
 Victoza | Use it during pregnancy only if the benefit justifies that possible risk for the baby. | daily injection |
| Byetta | There is not enough Pregnancy data to determine the risk; ask your doctor about it before you try to conceive. | twice-daily injection |
Sources: FDA label (DailyMed).
Questions to ask your prescriber
- How long before I try to conceive should I stop taking it?
- What should I do if I become pregnant while taking it?
See the complete Ozempic prescribing details on DailyMed.