Zepbound for Teens: Evidence, Eligibility, Coverage
No. Zepbound is not approved for anyone under 18. It is approved for adults only: weight loss and sleep apnea.
- For teens
- Adults only
- Active ingredient
- tirzepatide
- How it is taken
- weekly injection
Zepbound in brief
The half-life is 5 to 6 days. After 5.5 d, half is gone, and after five half-lives (27.5 d), about 3% remains.
In SURMOUNT-1, the 72-week result was 20.9% of body weight, compared with 3.1% for placebo.
Monthly prices in US dollars cover the list price and self-pay offers. Both figures are read from the maker's price page.
Sources: FDA label (DailyMed), Eli Lilly 1 2, cnbc.com.
Who qualifies?
| Source | Who qualifies |
|---|---|
| FDA label | With diet and activity, it supports weight loss and long-term weight maintenance for adults with obesity, and for adults who are overweight with a weight-related condition. |
| FDA label | It treats moderate to severe obstructive sleep apnea in adults with obesity. |
Sources: DailyMed FDA label.
What is different for teens?
| What changes | What the label says |
|---|---|
| Acute Gallbladder Disease | Gallstones and gallbladder inflammation can happen. Pain in the upper right belly, fever, or yellow skin or eyes should be reported. |
| Acute Pancreatitis | Can cause inflammation of the pancreas. If severe stomach pain continues, stop taking this medicine and get care. |
From the FDA labels: FDA label on DailyMed.
Warnings come from the DailyMed FDA label.
Coverage for teens
Alternatives for teens
| Medicine | For teens | How it is taken | Trial result |
|---|---|---|---|
| From age 12, for weight loss | weekly injection or daily tablet | 16.1% drop in BMI | |
| From age 10, for type 2 diabetes | weekly injection | Not listed | |
| From age 10, for type 2 diabetes | weekly injection | Not listed | |
| From age 12, for weight loss | daily injection | Not listed | |
| From age 10, for type 2 diabetes | daily injection | Not listed | |
| Adults only | weekly injection | Not listed | |
| Adults only | weekly injection | Not listed | |
| Adults only | daily tablet | Not listed | |
| Adults only | daily tablet | Not listed | |
| Byetta | Adults only | twice-daily injection | Not listed |
Sources: FDA label (DailyMed), PubMed.
Questions to ask your prescriber
- Has my child reached the required age on this medicine's label?
- What checks will track growth and eating?
- Suppose my child wants to stop. What then?
For complete prescribing information, see Zepbound details on DailyMed.