Zepbound Cost With Insurance: Typical Copays by Plan Type

With commercial insurance that covers it, the savings card can bring the copay down to $25 for up to a 3-month fill. If your plan does not cover it, the offer for that case is $299 a month. On Medicare, the GLP-1 Bridge copay is $50 a month.

List price: $499 to $1,086 per fill
Self-pay from: $299 a month
With a savings card: For up to a 3-month fill, you may pay as little as $25
Medicare: $50 a month

Zepbound cost with insurance varies with your copay and your plan's coverage for Zepbound. Medicare, the savings card, and the no-coverage offer are each governed differently.

Zepbound: a quick overview

Time in the body before it clears

Half clears from the body in 5 to 6 days: by 5.5 d, half is gone. About 3% remains following five half-lives (27.5 d).

Main trial weight loss

SURMOUNT-1 at 72 weeks showed 20.9% of body weight, compared with 3.1% on placebo.

Sources: FDA label (DailyMed).

Zepbound cost with insurance: the price table

Prices by route for Zepbound
Route	Who it is for	What you pay	Limits and dates
List price	Before insurance or any discount	$499 to $1,086 per fill	Not listed
Zepbound Savings Program	Commercially insured with Zepbound coverage; government plans excluded	For up to a 3-month fill, you may pay as little as $25	Up to $1,300 in savings per calendar year; each 1-month fill saves up to $100. Ends December 31, 2026
Zepbound offer for plans without Zepbound coverage	KwikPen 2.5 mg, commercial plan without coverage	$299 a month	Commercial plan without coverage: $499 a month for a single-dose pen
Medicare GLP-1 Bridge	Medicare Part D, for weight management	$50 a month	July 1, 2026 to December 31, 2027

Prices checked November 2026. Every price links to the page it came from.

Sources: pricinginfo.lilly.com, zepbound.lilly.com, Eli Lilly, TrumpRx.

How your copay works with the savings card

If your commercial plan covers Zepbound, the card can lower your copay to for up to a 3-month fill, you may pay as little as $25.
For each 1-month fill, the card covers no more than $100. Only part of a copay above that cap is covered.
Savings end once they hit $1,300 per calendar year.
The card now in use ends on December 31, 2026.
A separate offer costs $299 each month when your plan does not cover Zepbound.

Source: zepbound.lilly.com.

Does your plan cover it? How to check

Factors that affect Zepbound pricing

Your prescriber's chosen strength affects the self-pay price, which ranges from $299 to $449 a month.
Coupon prices: GoodRx says its own prices change often and vary by pharmacy.

Zepbound cost with insurance: a pharmacy receipt and a calculator

Source: investors.goodrx.com.

Lowest-cost Zepbound option for your coverage

The cheapest route for each coverage type
If you have	Cheapest route	You pay
Commercial insurance that covers it	Zepbound Savings Program	For up to a 3-month fill, you may pay as little as $25
Commercial insurance that does not cover it	Zepbound offer for plans without Zepbound coverage	$299 a month
No insurance	LillyDirect: LillyDirect vial or KwikPen 2.5 mg	$299 a month
Medicare	Medicare GLP-1 Bridge	$50 a month
Medicaid	Your state's Medicaid drug list decides	Zepbound and Medicaid by state

How Zepbound prices change over time

Changes in Zepbound pricing
Month	Price	What it was
November 2026	$499 to $1086.37 per fill	List price (list price range)
February 2026	$299 a month	Self-pay price (KwikPen or vial, 2.5 mg)
December 2025	$299 a month	Self-pay price (2.5 mg vial)
December 2025	$449 a month	Self-pay price (7.5 mg to 15 mg vials, Journey Program)
June 2025	$499 a month	Self-pay price (all vial doses, max)
February 2025	$349 a month	Self-pay price (2.5 mg vial)
February 2025	$499 a month	Self-pay price (7.5 mg and 10 mg vials, Journey Program)
August 2024	$399 a month	Self-pay price (2.5 mg vial)
November 2023	$1,059.87 per fill	List price (list price at launch)