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GLP-1 Decoder

Liraglutide for Teens: Evidence, Eligibility, Coverage

Yes, for some brands: Victoza from age 10 for type 2 diabetes and Saxenda from age 12 for weight loss.

Brands
Victoza and Saxenda

A brief look at Saxenda

How long it stays in your body
100%50%25%0%013 h26 h39 h2.2 d2.7 d50%25%12.5%time after the dose

Its half-life is about 13 hours. After 13 h, half is gone, and five half-lives leave about 3% (2.7 d).

Main trial weight loss results
Saxenda (SCALE Obesity and Prediabetes)7.4%Placebo3%

For Obesity and Prediabetes, 56 weeks, SCALE showed 7.4% of body weight, compared with 3% on placebo.

Label details: FDA label (DailyMed).

Who qualifies?

Which people qualify for liraglutide?
MedicineWho qualifies
VictozaFor adults and children 10 and older with type 2 diabetes, it helps lower blood sugar when used with diet and exercise.
VictozaFor adults with type 2 diabetes and heart disease, it lowers the risk of heart-related death, heart attack, and stroke.
SaxendaThis medicine helps with weight loss and keeping weight off long term, along with diet and activity. It is for adults and for children age 12 and older (over 60 kg) who have obesity, or for adults who have overweight along with a weight-related condition.

Label information: FDA label (DailyMed) 1 2.

What is different for teens?

Liraglutide: label points for teens
What changesWhat the label saysLabels
Acute PancreatitisCan cause inflammation of the pancreas. If your severe stomach pain does not go away, stop taking it and get medical care. The pain sometimes reaches your back.All of them
Acute Gallbladder DiseaseGallstones and gallbladder inflammation can happen. Report upper right belly pain. Also report a fever, yellow skin, or yellow eyes.All of them

According to the FDA labels: FDA label (DailyMed).

These warnings are from the label: FDA label (DailyMed).

Coverage for teens

Alternatives for teens

GLP-1 medicines and teens
MedicineFor teensHow it is takenTrial result
SaxendaFrom age 12, for weight lossdaily injectionNot listed
VictozaFrom age 10, for type 2 diabetesdaily injectionNot listed
WegovyFrom age 12, for weight lossweekly injection or daily tablet16.1% drop in BMI
MounjaroFrom age 10, for type 2 diabetesweekly injectionNot listed
TrulicityFrom age 10, for type 2 diabetesweekly injectionNot listed
OzempicAdults onlyweekly injectionNot listed
RybelsusAdults onlydaily tabletNot listed
ZepboundAdults onlyweekly injectionNot listed
FoundayoAdults onlydaily tabletNot listed
ByettaAdults onlytwice-daily injectionNot listed

Sources: FDA label (DailyMed), PubMed.

Questions to ask your prescriber