Zepbound While Breastfeeding: What the Human Milk Study Shows

The Zepbound label on breastfeeding: A small study found no measurable amount in breast milk, or only a low level.

Zepbound: quick facts

How long your body keeps it

Its half-life is 5 to 6 days. After 5.5 d, half is gone, and after five half-lives (27.5 d), about 3% remains.

Weight loss in its main trial

SURMOUNT-1 ran for 72 weeks and reported 20.9% for body weight, against 3.1% on placebo.

Cost over time

Monthly prices in US dollars include the list price and self-pay offers. Each comes from the maker's price page.

Zepbound label: breastfeeding
Medicine	What the label says
Zepbound	A small study found no measurable amount in breast milk, or only a low level.

FDA labels provide the details: label information on DailyMed.

These warnings come from the label: DailyMed FDA label details.

GLP-1 medicines and breastfeeding
Medicine	What the label says	How it is taken
Zepbound	A small study found no measurable amount in breast milk, or only a low level.	weekly injection
Ozempic	It is not known whether this medicine enters human breast milk.	weekly injection
Wegovy	Breast milk contains SNAC, and the tablets also contain it; for the injection, passage into breast milk is not known.	weekly injection or daily tablet
Rybelsus	Breast milk contains SNAC, and the tablets also contain it.	daily tablet
Mounjaro	A small study found no measurable amount in breast milk, or only a low level.	weekly injection
Foundayo	It is not known whether this medicine enters human breast milk.	daily tablet
Trulicity	It is not known whether this medicine enters human breast milk.	weekly injection
Saxenda	It is not known whether this medicine enters human breast milk.	daily injection
Victoza	It is not known whether this medicine enters human breast milk.	daily injection
Byetta	It is not known whether this medicine enters human breast milk.	twice-daily injection