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GLP-1 Decoder

Saxenda for Teens: Evidence, Eligibility, Coverage

Yes, from age 12: Saxenda is FDA approved for weight loss in children 12 and older.

For teens
From age 12, for weight loss
Active ingredient
liraglutide
How it is taken
daily injection

Saxenda in brief

How long it remains in the body
100%50%25%0%013 h26 h39 h2.2 d2.7 d50%25%12.5%time after the dose

About 13 hours is the half-life. After 13 h, half is gone, and about 3% remains at five half-lives, or 2.7 days.

Weight loss in the main trial
Saxenda (SCALE Obesity and Prediabetes)7.4%Placebo3%

For Prediabetes, 56 weeks, the SCALE Obesity trial showed 7.4% of body weight, compared with 3% on placebo.

Source: the FDA DailyMed label.

Who qualifies?

Saxenda: who qualifies
SourceWho qualifies
FDA labelThis covers adults and children aged 12 or older (over 60 kg) who have obesity, plus overweight adults who also have a weight-related condition. It focuses on long-term weight loss and maintenance with diet and activity.

Source: the FDA DailyMed label.

What is different for teens?

Saxenda: label points for teens
What changesWhat the label says
Acute PancreatitisCan cause inflammation of the pancreas. If severe stomach pain does not go away and sometimes spreads to the back, stop it and get care.
Acute Gallbladder DiseaseGallstones and gallbladder inflammation can happen. Report upper right belly pain, fever, or yellow skin or eyes.

The DailyMed FDA label provides this information.

The DailyMed FDA label lists these warnings.

Coverage for teens

Alternatives for teens

GLP-1 medicines and teens
MedicineFor teensHow it is takenTrial result
SaxendaFrom age 12, for weight lossdaily injectionNot listed
WegovyFrom age 12, for weight lossweekly injection or daily tablet16.1% drop in BMI
MounjaroFrom age 10, for type 2 diabetesweekly injectionNot listed
TrulicityFrom age 10, for type 2 diabetesweekly injectionNot listed
VictozaFrom age 10, for type 2 diabetesdaily injectionNot listed
OzempicAdults onlyweekly injectionNot listed
RybelsusAdults onlydaily tabletNot listed
ZepboundAdults onlyweekly injectionNot listed
FoundayoAdults onlydaily tabletNot listed
ByettaAdults onlytwice-daily injectionNot listed

Sources: FDA label on DailyMed and PubMed.

Questions to ask your prescriber

Read the full Saxenda prescribing information on DailyMed.