Rybelsus Liver: How Common, How Long It Lasts, What Helps
The Rybelsus label does not list liver effects as a side effect. What people mean by it: changes in liver blood tests or liver problems.
- In the label
- Not listed
- Most common in the label
- Nausea 20%
Rybelsus: a quick overview
After five half-lives (35 d), about 3% remains; its half-life is about 1 week, so half is gone after 7 d.
In PIONEER 1, people with type 2 diabetes lost 3.7 kg over 26 weeks, compared with 1.4 kg on placebo.
Each month’s prices are shown in US dollars. They cover list price and self-pay offers read from the manufacturer's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, Novo Nordisk pricing, Novo Nordisk.
What the Rybelsus label lists instead
The Rybelsus label does not list liver effects. These five side effects appear most often on the label.
| Side effect | Placebo | Rybelsus 7 mg | Rybelsus 14 mg | More than placebo, 14 mg |
|---|---|---|---|---|
| Nausea | 6% | 11% | 20% | +14 points |
| Abdominal Pain | 4% | 10% | 11% | +7 points |
| Diarrhea | 4% | 9% | 10% | +6 points |
| Decreased appetite | 1% | 6% | 9% | +8 points |
| Vomiting | 3% | 6% | 8% | +5 points |
Source: Rybelsus label (DailyMed).
Source: FDA label (DailyMed).