Rybelsus for Breastfeeding: Evidence, Eligibility, Coverage
The Rybelsus label on breastfeeding: The tablets and breast milk both contain SNAC.
- Active ingredient
- semaglutide
- How it is taken
- daily tablet
Rybelsus in brief
Its half-life is about 1 week: after 7 d, half is gone, and after five half-lives (35 d), about 3% remains.
In PIONEER 1, people with type 2 diabetes lost 3.7 kg over 26 weeks. Placebo resulted in a loss of 1.4 kg.
Monthly prices in US dollars show the list price and self-pay offers. Each one is listed on the maker's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, Novo Nordisk pricing, Novo Nordisk.
Breastfeeding advice in the Rybelsus label
| Medicine | What the label says |
|---|---|
| Rybelsus | The tablets and breast milk both contain SNAC. |
The FDA label (DailyMed) provides these details.
These warnings come from the FDA label (DailyMed).
Each GLP-1 label on breastfeeding
| Medicine | What the label says | How it is taken |
|---|---|---|
| Rybelsus | The tablets and breast milk both contain SNAC. | daily tablet |
 Ozempic | It is unknown whether this medicine enters human breast milk. | weekly injection |
 Wegovy | The tablets and breast milk both contain SNAC; for the injection, passage into breast milk is not known. | weekly injection or daily tablet |
 Mounjaro | A small study found undetectable or low levels in breast milk. | weekly injection |
 Zepbound | A small study found undetectable or low levels in breast milk. | weekly injection |
 Foundayo | It is unknown whether this medicine enters human breast milk. | daily tablet |
 Trulicity | It is unknown whether this medicine enters human breast milk. | weekly injection |
 Saxenda | It is unknown whether this medicine enters human breast milk. | daily injection |
 Victoza | It is unknown whether this medicine enters human breast milk. | daily injection |
| Byetta | It is unknown whether this medicine enters human breast milk. | twice-daily injection |
Source: FDA label (DailyMed).
Questions to ask your prescriber
- While I am breastfeeding, is there an option that has been studied more?
- Would you advise me to wait until I have weaned?
Read Rybelsus information on DailyMed for all prescribing details.