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GLP-1 Decoder

GLP-1s and Breastfeeding: ACOG Guidance, Milk Data by Drug

7 of 10 GLP-1 labels say it is not known whether the medicine passes into breast milk. The Mounjaro and Zepbound labels cite a small study where levels in breast milk were undetectable or low.

Half-life and weight loss overview

How long each medicine stays in your body
Wegovy7 dOzempic7 dRybelsus7 dZepbound5.5 dMounjaro5 dTrulicity5 dFoundayo1.6 dSaxenda0.5 dVictoza0.5 dByetta0.1 d

In days, half-life shows how long the body needs to clear half a dose. The figure comes from 12.3 in each FDA label.

How much weight was lost in the main weight trial for each medicine
Zepbound20.9%Wegovy14.9%Foundayo11.1%Saxenda7.4%

Percentage of body weight. Because trials, doses, and time periods vary, compare each result with the placebo on its own page.

Sources (10)

DailyMed FDA labels: 1 2 3 4 5 6 7 8 9 10.

Each GLP-1 label on breastfeeding

GLP-1 medicines and breastfeeding
MedicineWhat the label saysHow it is taken
OzempicIt is not known if the medicine passes into human breast milk.weekly injection
WegovySNAC is present in breast milk and tablets. It is not known whether the injected form passes into breast milk.weekly injection or daily tablet
RybelsusThe tablets contain SNAC, and breast milk contains it as well.daily tablet
MounjaroA small study found breast milk levels that were undetectable or low.weekly injection
ZepboundA small study found breast milk levels that were undetectable or low.weekly injection
FoundayoIt is not known if the medicine passes into human breast milk.daily tablet
TrulicityIt is not known if the medicine passes into human breast milk.weekly injection
SaxendaIt is not known if the medicine passes into human breast milk.daily injection
VictozaIt is not known if the medicine passes into human breast milk.daily injection
ByettaIt is not known if the medicine passes into human breast milk.twice-daily injection

Sources: FDA label (DailyMed).

Warnings from the FDA (DailyMed) label.

Questions for your prescriber