Semaglutide for Breastfeeding: Evidence, Eligibility
The Semaglutide label on breastfeeding: It is not known whether it enters human breast milk.
- Brands
- Ozempic, Wegovy and Rybelsus
Wegovy in brief
About 1 week is the half-life: by 7 d, half is gone, and about 3% remains after five half-lives (35 d).
In STEP 1, people lost 14.9% of body weight over 68 weeks, compared with 2.4% on placebo.
Monthly price points in US dollars cover the list price plus self-pay offers, with each figure taken from the maker's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.
The label on breastfeeding
| Medicine | What the label says |
|---|---|
 Ozempic | It is not known whether it enters human breast milk. |
 Wegovy | The tablets contain SNAC, and breast milk also contains it; for the injection, passage into breast milk is not known. |
 Rybelsus | The tablets contain SNAC, and breast milk also contains it. |
The FDA labels say this, and DailyMed label details are here: 1 2 3.
These warnings are taken from the label: FDA label (DailyMed).
Each GLP-1 label on breastfeeding
| Medicine | What the label says | How it is taken |
|---|---|---|
| Ozempic | It is not known whether it enters human breast milk. | weekly injection |
| Wegovy | The tablets contain SNAC, and breast milk also contains it; for the injection, passage into breast milk is not known. | weekly injection or daily tablet |
| Rybelsus | The tablets contain SNAC, and breast milk also contains it. | daily tablet |
 Mounjaro | A small study found amounts in breast milk that were not detectable, or that were low. | weekly injection |
 Zepbound | A small study found amounts in breast milk that were not detectable, or that were low. | weekly injection |
 Foundayo | It is not known whether it enters human breast milk. | daily tablet |
 Trulicity | It is not known whether it enters human breast milk. | weekly injection |
 Saxenda | It is not known whether it enters human breast milk. | daily injection |
 Victoza | It is not known whether it enters human breast milk. | daily injection |
| Byetta | It is not known whether it enters human breast milk. | twice-daily injection |
Sources: DailyMed FDA label.
Ask your prescriber these questions
- While I am breastfeeding, is there an option that has been studied more?
- Do you think it would be better to wait until I have weaned?